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Adaptation of SIVmac to baboon primary cells results in complete absence of in vivo baboon infectivity

Veronica Obregon-Perko, Amanda Mannino, Jason T. Ladner, Vida Hodara et al. • Frontiers in Cellular and Infection Microbiology (2024)

While simian immunodeficiency virus (SIV) infection is non-pathogenic in naturally infected African nonhuman primate hosts, experimental or accidental infection in rhesus macaques often leads to AIDS. Baboons, widely distributed throughout ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2024.1408245

Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii

Joachim Kloehn, Rebecca D. Oppenheim, Ghizal Siddiqui, Pieter-Jan De Bock et al. • BMC Biology (2020)

Abstract Background Acetyl-CoA is a key molecule in all organisms, implicated in several metabolic pathways as well as in transcriptional regulation and post-translational modification. The human pathogen Toxoplasma gondii possesses at leas...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12915-020-00791-7

Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson’s Disease

Stewart F. Graham, Nolwen L. Rey, Zafer Ugur, Ali Yilmaz et al. • Metabolites (2018)

For people with Parkinson’s disease (PD), considered the most common neurodegenerative disease behind Alzheimer’s disease, accurate diagnosis is dependent on many factors; however, misdiagnosis is extremely common in the prodrom...

DOAJ Open Access (DOAJ) DOI: 10.3390/metabo8040071

Evolution of the tripartite symbiosis between earthworms, Verminephrobacter and Flexibacter-like bacteria

Peter eMøller, Marie Braad Lund, Andreas eSchramm • Frontiers in Microbiology (2015)

Nephridial (excretory organ) symbionts are widespread in lumbricid earthworms and the complexity of the nephridial symbiont communities varies greatly between earthworm species. The two most common symbionts are the well-described Vermineph...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2015.00529

An assessment of the mathematical model for estimating of entropy optimized viscous fluid flow towards a rotating cone surface

Yong-Min Li, M. Ijaz Khan, Sohail A. Khan, Sami Ullah Khan et al. • Scientific Reports (2021)

Abstract Entropy optimization in convective viscous fluids flow due to a rotating cone is explored. Heat expression with heat source/sink and dissipation is considered. Irreversibility with binary chemical reaction is also deliberated. Nonl...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-89739-7

Optimized two-stage process of Haematococcus sp. for enhanced astaxanthin and essential fatty acids accumulation

Pablo N. Refolio-Samperi, Elena Adaschewski, Dieter Hanelt, Abdelfatah Abomohra • Applied Food Research (2025)

The present study evaluated a two-stage process of Haematococcus sp. to enhance the nutritional value by astaxanthin and fatty acid accumulation. Initial screening of different growth media during the green stage, focusing on enhanced bioma...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.afres.2025.101144

Post-fire forest management effects on soil metal dynamics in Mediterranean forests

Yener Ulus, Yener Ulus, Shaoyi Wang, Shaoyi Wang et al. • Frontiers in Environmental Science (2025)

Wildfires are an integral component of Mediterranean ecosystems. The forest management practices implemented following such forest fires can significantly influence soil chemistry and metal dynamics. This study investigates the effects of d...

DOAJ Open Access (DOAJ) DOI: 10.3389/fenvs.2025.1661652

Molecular regionalization in the compact brain of the meiofaunal annelid Dinophilus gyrociliatus (Dinophilidae)

Alexandra Kerbl, José M. Martín-Durán, Katrine Worsaae, Andreas Hejnol • EvoDevo (2016)

Abstract Background Annelida is a morphologically diverse animal group that exhibits a remarkable variety in nervous system architecture (e.g., number and location of longitudinal cords, architecture of the brain). Despite this heterogeneit...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13227-016-0058-2

A Novel Anticancer Peptide Derived from <i>Bryopsis plumosa</i> Regulates Proliferation and Invasion in Non-Small Cell Lung Cancer Cells

Heabin Kim, Hyun-Taek Kim, Seung-Hyun Jung, Jong Won Han et al. • Marine Drugs (2023)

The discovery of new highly effective anticancer drugs with few side effects is a challenge for drug development research. Natural or synthetic anticancer peptides (ACPs) represent a new generation of anticancer agents with high selectivity...

DOAJ Open Access (DOAJ) DOI: 10.3390/md21120607

Varieties of Mushrooms and their Nutraceutical Importance: A Systematic Review

Debasmita Chatterje, Dipankar Halder, Satadal Das • Journal of Clinical and Diagnostic Research (2021)

Introduction: Around 2000 species of mushrooms exist in nature, of which hardly 25 varieties are accepted as edible in nature. “Nutraceuticals” are food substances that are associated with immense health benefits and also hinder the deve...

DOAJ Open Access (DOAJ) DOI: 10.7860/JCDR/2021/47240.14660

Critical Analysis of the Development of the Design of Lattice Tube Concrete Bridges with a Ride on Top

D. S. Spivak, S. V. Kliuchnyk • Nauka ta progres transportu (2024)

Purpose. The paper aims to highlight and substantiate the need to find rational design schemes for lattice tube concrete bridges with a ride on top based on the analysis of recent research and regulatory documents. Methodology. The current ...

DOAJ Open Access (DOAJ) DOI: 10.15802/stp2024/301524

Rapid fabrication of CuMoO4 nanocomposites via electric field assisted pulsed-laser ablation in liquids for electrochemical hydrogen generation

Chaudry Sajed Saraj, Subhash C. Singh, Gopal Verma, Amged Alquliah et al. • Applied Surface Science Advances (2023)

Transition–metal-doped electrocatalysts are considered as low-cost alternatives of Pt and RuO2 electrocatalysts for large scale electrochemical generations of hydrogen and oxygen, respectively. Although, chemical synthesis, typically adopte...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.apsadv.2022.100358

The impact of phase change material on photovoltaic thermal (PVT) systems: A numerical study

Sameh Alsaqoor, Ahmad Alqatamin, Ali Alahmer, Zhang Nan et al. • International Journal of Thermofluids (2023)

This study examines the impact of incorporating phase change material (PCM) in photovoltaic thermal (PVT) systems on their electrical and thermal performance. Although PVT systems have shown effectiveness in converting solar energy into bot...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijft.2023.100365

Efficient generation of P53 biallelic knockout Diannan miniature pigs via TALENs and somatic cell nuclear transfer

Youfeng Shen, Kaixiang Xu, Zaimei Yuan, Jianxiong Guo et al. • Journal of Translational Medicine (2017)

Abstract Background Pigs have many features that make them attractive as biomedical models for various diseases, including cancer. P53 is an important tumor suppressor gene that exerts a central role in protecting cells from oncogenic trans...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12967-017-1327-0

Strategies for Supporting Child Development and Care amidst Financial Distress: A Scoping Review

Chiamaka Pamela Uchendu, Ezeda Patricia Kalu • International Journal of Home Economics, Hospitality and Allied Research (2025)

Recognizing the profound impact of economic hardship on children's well-being, this research used a scoping review approach to explore strategies for supporting child development and care amidst financial distress. An extensive search was p...

DOAJ Open Access (DOAJ) DOI: 10.57012/ijhhr.v4n1.018

Exploring resilience among hospital workers: a Bayesian approach

Laura Uccella, Ilenia Mascherona, Sebastiano Semini, Sara Uccella et al. • Frontiers in Public Health (2024)

Background and importanceHealthcare professionals face significant workloads, as their roles are among the most demanding and stressful. Resilience serves as a crucial factor in helping them cope with the challenges encountered in their wor...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2024.1403721