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S1 Subunit of Spike Protein from a Current Highly Virulent Porcine Epidemic Diarrhea Virus Is an Important Determinant of Virulence in Piglets

Tohru Suzuki, Yutaka Terada, Luis Enjuanes, Seiichi Ohashi et al. • Viruses (2018)

Base on the sequence of S genes, which encode spike proteins, we previously identified three different types (North American, S INDEL, and S large-DEL types) of porcine epidemic diarrhea virus (PEDV) that have re-emerged in Japan since 2013...

DOAJ Open Access (DOAJ) DOI: 10.3390/v10090467

Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford progeria syndrome

Florian Köhler, Felix Bormann, Günter Raddatz, Julian Gutekunst et al. • Genome Medicine (2020)

Abstract Background Hutchinson-Gilford progeria syndrome (HGPS) is a progeroid disease characterized by the early onset of age-related phenotypes including arthritis, loss of body fat and hair, and atherosclerosis. Cells from affected indiv...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13073-020-00749-y

Molecular Biology of the Gene

James Dewey Watson • Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory) (1970)

The long-awaited Fifth Edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA doub...

OPENALEX

Molecular Biology of the Cell

Bruce Alberts, Alexander D. Johnson, Julian Herman Lewis, MARTIN C. RAFF et al. • W.W. Norton eBooks (2007)

For nearly a quarter century Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advan...

OPENALEX DOI: https://doi.org/10.1201/9780203833445

Innovative green niosomal piperlongumine as a novel topical treatment for dermatophytosis in guinea pigs model

Iman Haghani, Abbas Raeisabadi, Javad Akhtari, Aylar Arbabi et al. • Scientific Reports (2025)

Abstract Dermatophytosis is a common superficial fungal infection that affects many people worldwide. Although various species of dermatophytes respond to common antifungal drugs, the recently identified Trichophyton indotineae isolates hav...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-21729-5

Effect of angiotensin-converting enzyme gene polymorphism at the results of losartan use in the patients with type 2 diabetes mellitus

T. Yu. Poniatowskaya • Journal of Education, Health and Sport (2015)

Poniatowskaya T. Yu. Effect of angiotensin-converting enzyme gene polymorphism at the results of losartan use in the patients with type 2 diabetes mellitus. Journal of Education, Health and Sport. 2015;5(3):55-61. ISSN 2391-8306. DOI: 10.52...

DOAJ Open Access (DOAJ)

Synthetic biology open language (SBOL) version 3.1.0

Buecherl Lukas, Mitchell Thomas, Scott-Brown James, Vaidyanathan Prashant et al. • Journal of Integrative Bioinformatics (2023)

Synthetic biology builds upon genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. When designing a synthetic system, synthetic biologists need to exchange informatio...

DOAJ Open Access (DOAJ) DOI: 10.1515/jib-2022-0058

Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors

Safwaan H. Khan, Safwaan H. Khan, Yeonjoo Choi, Mysore Veena et al. • Frontiers in Immunology (2025)

Chimeric antigen receptor (CAR) T cell therapy has revolutionized the treatment of hematologic malignancies, achieving remarkable clinical success with FDA-approved therapies targeting CD19 and BCMA. However, the extension of these successe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2024.1489827

The Human dsRNA binding protein PACT is unable to functionally substitute for the Drosophila dsRNA binding protein R2D2 [v1; ref status: indexed, http://f1000r.es/201]

Benjamin K Dickerman, Jocelyn A McDonald, Ganes C Sen • F1000Research (2013)

The primary function of the dsRNA binding protein (dsRBP) PACT/RAX is to activate the dsRNA dependent protein kinase PKR in response to stress signals.  Additionally, it has been identified as a component of the small RNA processing pathway...

DOAJ Open Access (DOAJ) DOI: 10.12688/f1000research.2-220.v1

Worldwide productivity and research trend of publications concerning extracellular vesicles role in fibrosis: A bibliometric study from 2013 to 2022

Ya-Wen Peng, Ri Tang, Qiao-Yi Xu, Shu-Ya Mei et al. • Heliyon (2024)

Background: Fibrosis is a heavy burden on the global healthcare system. Recently, an increasing number of studies have demonstrated that Extracellular vesicles play an important role in intercellular communication under both physiological a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2024.e24357

International Archives of Allergy and Immunology

• International Archives of Allergy and Immunology (2015)

International Archives of Allergy and Immunology provides a forum for experimental and clinical research in modern molecular and cellular allergology and immunology. Appearing monthly, the journal publishes original work in the fields of al...

OPENALEX DOI: https://doi.org/10.1159/issn.1018-2438

Current Protocols in Immunology

• Current Protocols in Immunology (2018)

Current Protocols in Immunology is a three-volume looseleaf manual that provides comprehensive coverage of immunological methods from classic to the most cutting edge, including antibody detection and preparation, assays for functional acti...

OPENALEX DOI: https://doi.org/10.1002/(issn)1934-368x

The Advances of Single-Cell RNA-Seq in Kidney Immunology

Honghui Zeng, Honghui Zeng, Xiaoqiang Yang, Xiaoqiang Yang et al. • Frontiers in Physiology (2021)

Kidney diseases are highly prevalent and treatment is costly. Immune cells play important roles in kidney diseases; however, it has been challenging to investigate the contribution of each cell type in kidney pathophysiology. Recently, the ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphys.2021.752679

Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer

Ruifang Li, Sara A. Grimm, Deepak Mav, Haiwei Gu et al. • Cell Reports (2018)

Colorectal cancer (CRC) tends to occur at older age; however, CRC incidence rates have been rising sharply among young age groups. The increasing prevalence of obesity is recognized as a major risk, yet the mechanistic underpinnings remain ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.celrep.2017.12.071

Knockout of

Tushar K. Dutta, Voodikala S. Akhil, Utkarsh Chauhan, Prolay K. Bhowmick et al. • Rice Science (2026)

Direct-seeded rice (DSR) offers a sustainable alternative for climate-resilient agriculture, but it is severely threatened by the root-knot nematode Meloidogyne graminicola . Knockout of susceptibility (S) genes has emerged as a promising s...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rsci.2026.05.008

Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish

Marjo J. den Broeder, Jarle Ballangby, Leonie M. Kamminga, Peter Aleström et al. • Epigenetics & Chromatin (2020)

Abstract Background Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases. This susceptibility may in part be caused by changes to the epigenetic landscape which conseq...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13072-020-0329-y

Dietary effects of protein and lipid levels on growth performance and flesh quality of large-size largemouth bass (Micropterus salmoides)

Yunfeng Chen, Hang Yang, Beibei Guo, Xiaoqin Li et al. • Aquaculture Reports (2023)

The aim of this trial was to investigate the effects of dietary protein and lipid levels on growth performance and flesh quality of largemouth bass (Micropterus salmoides). A 3 × 3 two-factor design was used, including three crude protein l...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aqrep.2023.101852

Induced Pluripotent Stem Cells (iPSCs)—Roles in Regenerative Therapies, Disease Modelling and Drug Screening

Mourad A. M. Aboul-Soud, Alhusain J. Alzahrani, Amer Mahmoud • Cells (2021)

The discovery of induced pluripotent stem cells (iPSCs) has made an invaluable contribution to the field of regenerative medicine, paving way for identifying the true potential of human embryonic stem cells (ESCs). Since the controversy aro...

DOAJ Open Access (DOAJ) DOI: 10.3390/cells10092319

Co-Regulation of Protein Coding Genes by Transcription Factor and Long Non-Coding RNA in SARS-CoV-2 Infected Cells: An In Silico Analysis

Chinmay Saha, Sayantan Laha, Raghunath Chatterjee, Nitai P. Bhattacharyya • Non-Coding RNA (2021)

Altered expression of protein coding gene (PCG) and long non-coding RNA (lncRNA) have been identified in SARS-CoV-2 infected cells and tissues from COVID-19 patients. The functional role and mechanism (s) of transcriptional regulation of de...

DOAJ Open Access (DOAJ) DOI: 10.3390/ncrna7040074