Academic Articles & Research Papers

Anti-Tick-Borne Encephalitis Virus Activity of Novel Uridine Glycoconjugates Containing Amide or/and 1,2,3-Triazole Moiety in the Linker Structure

Tick-borne encephalitis virus (TBEV) transmitted by ticks is a pathogen of great medical importance. As still no effective antiviral treatment is available, in the present study, a series of uridine glycoconjugates containing amide or/and 1...

Selective green removal of arsenic from wet-process phosphoric acid using marine-derived Neptune ball Fibres

Abstract Phosphoric acid is the second most widely produced mineral acid worldwide and is predominantly manufactured via the wet process. However, wet-process phosphoric acid (WPPA) contains significant levels of dissolved and suspended imp...

Continuous monitoring biosensors for advanced healthcare and environmental applications: challenges, material innovations and future directions

This review critically discusses the development of continuous monitoring biosensors and the technological developments that have facilitated the transition from one-off or periodic measurement sensors to longer-term, connected and autonomo...

A renaissance of neural networks in drug discovery

INTRODUCTION: Neural networks are becoming a very popular method for solving machine learning and artificial intelligence problems. The variety of neural network types and their application to drug discovery requires expert knowledge to cho...

Laser-induced porous graphene electrodes from polyketimine membranes for paracetamol sensing

The development of cost-effective materials for fabricating electrodes is crucial for drug, pharmaceutical and environmental applications. This paper presents the synthesis and characterization of a novel polyketimine (PKI) membrane obtaine...

P2′ Site Scanning of Snake Kunitz-Type Toxin Analogue BF9-N17H with Unique P1 Site Histidine Highlights Novel XIa Inhibitory Peptides Without Plasmin Inhibitory Activity

Kunitz-type peptides from venomous and blood-sucking animals represent an important natural molecular resource for anticoagulant development towards XIa, a new target for antithrombotic drug discovery. However, the plasmin-inhibitory activi...

Electrorefining behavior of a multicomponent copper alloy derived from waste printed circuit boards

Efficient recycling of waste electrical and electronic equipment (WEEE) is a major priority for the circular economy and sustainable resource management. This study proposes and investigates an integrated mechanical, pyrometallurgical, and ...

Surface-State-Driven Selectivity of Electrocatalytic Glucose Oxidation: Metallic Au, Au─OH, and CuO.

Diminished Auditory Responses during NREM Sleep Correlate with the Hierarchy of Language Processing.

Natural sleep provides a powerful model system for studying the neuronal correlates of awareness and state changes in the human brain. To quantitatively map the nature of sleep-induced modulations in sensory responses we presented participa...

Machine Learning for Computational Heterogeneous Catalysis

Abstract Big data and artificial intelligence has revolutionized science in almost every field – from economics to physics. In the area of materials science and computational heterogeneous catalysis, this revolution has led to the developme...

Directed Evolution of Near-Infrared Serotonin Nanosensors with Machine Learning-Based Screening

In this study, we employed a novel approach to improve the serotonin-responsive ssDNA-wrapped single-walled carbon nanotube (ssDNA-SWCNT) nanosensors, combining directed evolution and machine learning-based prediction. Our iterative optimiz...

A selectivity filter in Tim17 mediates intramitochondrial protein sorting.

Directions of application of artificial intelligence in digital marketing communications

The digital transformation of modern economic life has found its reflection in the field of marketing communications, having formed a virtually new form of communication between market entities-digital. A distinctive feature of this form is...