Academic Articles & Research Papers

Dengue serotype immune-interactions and their consequences for vaccine impact predictions

Dengue is one of the most important and wide-spread viral infections affecting human populations. The last few decades have seen a dramatic increase in the global burden of dengue, with the virus now being endemic or near-endemic in over 10...

Mathematics and Visualization

Professionalising health technology assessment in South Africa

Health technology encompasses interventions developed to prevent, diagnose or treat medical conditions; promote health; provide rehabilitation or organise healthcare delivery. The intervention can be a test, device, medicine, vaccine, proce...

Digital prevention of depression for farmers? A qualitative study on participants' experiences regarding determinants of acceptance and satisfaction with a tailored guided internet intervention program

Introduction: Farmers, forest workers and gardeners have a higher risk of developing depression compared to other occupational populations. As part of the German pilot project “With us in balance”, the potential of six guided internet- and ...

Adopting AI Enhances Humanitarian Operations While Demanding Critical Trade-Offs

Artificial intelligence (AI) is increasingly impacting the cooperation sector, transforming how humanitarians are operating in the field. AI tools now allow for improved health diagnostics and quality services. In conflict areas, organizati...

Wellbeing intervention for chronic kidney disease (WICKD): a randomised controlled trial study protocol

Abstract Background Incidence of end stage kidney disease (ESKD) for Indigenous Australians is especially high in remote and very remote areas of Australia (18 and 20 times the rate of comparable non-Indigenous people). Relocating away from...

A “P5” Approach to Healthcare and Health Technology

Abstract The challenges represented by chronic conditions worldwide are related to disease management and patient engagement. Healthcare should open not only to new tools and resources but also to innovative approaches. This contribution de...

Reflections on the evolution of health technology assessment in Europe

Health technology assessment (HTA) has assumed an increasing role in health systems in recent years, with many countries establishing agencies or programmes to evaluate health technology and other interventions to inform policy decisions an...

Effectiveness of a tele-rehabilitation intervention to improve performance and reduce morbidity for people post hip fracture - study protocol for a randomized controlled trial

Abstract Background Most surviving hip-fracture patients experience reduced mobility and lose some of their functional ability, which increases the risk of complications and rehospitalization. Post-discharge transitional programs to reduce ...

Gender, power, and digital health inequities: a narrative review of barriers to digital health access among women in Lesotho

Digital health technologies are increasingly recognised as tools to enhance healthcare accessibility in resource-constrained settings. However, evidence suggests that not every section of society has benefitted equally. Women in developing ...

Factors associated with adolescent use of tobacco products in the Upper East Region of Ghana: A cross-sectional study

Introduction Tobacco use among adolescents is a concern in the Upper East Region of Ghana. We estimated the prevalence and identified factors contributing to single and multiple use of tobacco products among junior high school students in G...

Health Technology Assessment. Methodologies for Developing Countries

Evaluative research in area of health technology assessment (HTA) and training of researchers in medicine schools of public health and training programs in health management should be promoted. The focus when evaluating health technology in...

Health technology assessment and haemophilia

Although the funding of rare diseases such as haemophilia in developing countries remains a low priority, pressures on the funding of haemophilia treatment are also emerging in developed economies affected by the global economic downturn an...

A self-control training app to increase self-control and reduce aggression – A full factorial design

Background: Research has shown that self-control training (SCT) is an effective intervention to increase self-control and behaviour driven by self-control, such as reactive aggression. We developed an app that offers SCT by asking users to ...

Social norms, misperceptions, and mosquito net use: a population-based, cross-sectional study in rural Uganda

Abstract Background Mosquito net use is an essential part of malaria prevention. Although previous research has shown that many people sleep under a mosquito net in endemic areas, it is unknown whether people underestimate how common it is ...

Neurotoxicity of PM_2.5-Bound Multi-Pollutant Mixtures in Parkinson’s Disease: Exploring the <i>INPP5D</i>/SHIP1-PI3K-AKT Axis via an Integrative Multi-Omics Study

Accumulating epidemiological evidence links ambient PM2.5 exposure to elevated Parkinson’s disease (PD) risk, yet the neurotoxicity triggered by PM2.5 multi-pollutant mixtures under real co-exposure scenarios remains insufficiently elucidat...

Narratives of risk: Women at midlife, medical 'experts' and health technologies

The 'management' of midlife women's bodies is becoming an increasingly important focus for both themselves and medical 'experts'. Health technologies play a major part in this process, given health promotion messages about their usefulness ...

Treatment of Gluteal Tendinopathy: A Systematic Review and Stage-Adjusted Treatment Recommendation

Background: Gluteal tendinopathy is the most common lower limb tendinopathy. It presents with varying severity but may cause debilitating lateral hip pain. Purpose: To review the therapeutic options for different stages of gluteal tendinopa...

Parental Birth-Related PTSD Symptoms and Bonding in the Early Postpartum Period: A Prospective Population-Based Cohort Study

The parent-infant bond following childbirth is an important facilitator of optimal infant development. So far, research has mainly focused on mother-infant bonding. Data on fathers are still sparse. Parental mental health, such as posttraum...

Health technology assessment

Health technology assessment (HTA) provides information about the effectiveness, costs and broader impact of health technologies to those who plan, administer or receive care in the national health system. ''Technology'' includes all interv...