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Developing a Rational, Optimized Product of Centella asiatica for Examination in Clinical Trials: Real World Challenges

Kirsten M. Wright, Janis McFerrin, Armando Alcázar Magaña, Armando Alcázar Magaña et al. • Frontiers in Nutrition (2022)

Botanical products are frequently sold as dietary supplements and their use by the public is increasing in popularity. However, scientific evaluation of their medicinal benefits presents unique challenges due to their chemical complexity, i...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2021.799137

Identification of DDIT4 as a potential prognostic marker associated with chemotherapeutic and immunotherapeutic response in triple-negative breast cancer

Xuanzhao Chen, Zeyan Li, Meihua Liang, Ziyang Zhang et al. • World Journal of Surgical Oncology (2023)

Abstract Background Triple-negative breast cancer (TNBC) is the most heterogenous and aggressive subtype of breast cancer. Chemotherapy remains the standard treatment option for patients with TNBC owing to the unavailability of acceptable t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12957-023-03078-7

Caenorhabditis elegans Neurotoxicity Testing: Novel Applications in the Adverse Outcome Pathway Framework

Shreesh Raj Sammi, Shreesh Raj Sammi, Laura E. Jameson, Kendra D. Conrow et al. • Frontiers in Toxicology (2022)

Neurological hazard assessment of industrial and pesticidal chemicals demands a substantial amount of time and resources. Caenorhabditis elegans is an established model organism in developmental biology and neuroscience. It presents an idea...

DOAJ Open Access (DOAJ) DOI: 10.3389/ftox.2022.826488

Exploring resilience among hospital workers: a Bayesian approach

Laura Uccella, Ilenia Mascherona, Sebastiano Semini, Sara Uccella et al. • Frontiers in Public Health (2024)

Background and importanceHealthcare professionals face significant workloads, as their roles are among the most demanding and stressful. Resilience serves as a crucial factor in helping them cope with the challenges encountered in their wor...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2024.1403721

Operational Labor Shortages and Authentic Hospitality: Evidence from Greek Hotels

Georgios Konstantopoulos, Grigoris Giannarakis, Maria Xenaki, Georgios Thanasas et al. • Tourism and Hospitality (2026)

Operational labor shortages have become a pressing challenge for hospitality organizations, especially in highly seasonal tourism destinations such as Greece, where service experiences are deeply tied to cultural identity and authentic hosp...

DOAJ Open Access (DOAJ) DOI: 10.3390/tourhosp7060180

Poster 58. Preoperative Corticosteroid Injection History Does Not Influence Meniscal Allograft Transplantation Survivorship or Failure Rates

Vishal Sundaram, Isabella Jazrawi BA, Rushani K. Cameron MS, Cody Perskin et al. • Orthopaedic Journal of Sports Medicine (2026)

Objective: Meniscal allograft transplantation (MAT) is a joint-preserving option for patients with symptomatic meniscal deficiency unresponsive to nonoperative care. By restoring tibiofemoral load transmission, MAT can relieve pain, improve...

DOAJ Open Access (DOAJ) DOI: 10.1177/2325967126S00369

Prophylactic Absorbable Antibiotic Beads for High-risk, Implant-based Prepectoral Reconstruction

Shahnur Ahmed, MD, Jason T. C. Lee, MD, MSc, Dylan Roth, BS, Mithun Sinha, PhD et al. • Plastic and Reconstructive Surgery, Global Open (2023)

Summary:. Infections are problematic in postmastectomy implant-based reconstruction with infection rates as high as 30%. Strategies to reduce the risk of infection have demonstrated various efficacies. A prolonged course of systemic, oral a...

DOAJ Open Access (DOAJ) DOI: 10.1097/GOX.0000000000005353

Sedative-hypnotic drug use and risk of falls and fractures in elderly patients: a cross-sectional study

Mohammad Hossein Imani, Amir Hossein Imani, Amirhossein Saem, Maryam Niksolat • BMC Geriatrics (2025)

Abstract Background Falls are a leading cause of injury, hospitalization, and mortality among older adults. Sedative-hypnotic medications, especially benzodiazepines and Z-drugs, have been implicated as potential contributors to fall risk a...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-025-06624-y

CSR and CEO’s Moral Reasoning in the Automotive Industry in the Era of COVID-19

Beatriz Garcia-Ortega, Javier Galan-Cubillo, Blanca de-Miguel-Molina • SAGE Open (2022)

This paper assesses whether and to which extent the COVID-19 pandemic, which represents a scenario of high moral intensity, is influencing the moral reasoning of top CEOs (chief executive officers) in the paradigmatic case of the automotive...

DOAJ Open Access (DOAJ) DOI: 10.1177/21582440221097377

Non-traumatic Causes of Brown-sequard Syndrome: A Case Series and Clinical Update With Systematic Review

Vaner Köksal, Mahmoud Osama, Mohammed Ali Alvi • Iranian Journal of Neurosurgery (2021)

Background and Importance: Brown-Sequard Syndrome (BSS) is a rare neurological condition resulting from a hemisection injury to or unilateral compression on the spinal cord. The common causes of BSS that are amenable to be treated surgicall...

DOAJ Open Access (DOAJ)

Procalcitonin-guided antibiotic therapy for pediatrics with infective disease: A updated meta-analyses and trial sequential analysis

Peng Li, JiaLe Liu, Junjun Liu • Frontiers in Cellular and Infection Microbiology (2022)

ObjectiveWe aimed to evaluate the effect of procalcitonin (PCT) guided therapy on antibiotic exposure in pediatric patients with infectious disease.MethodsWe performed an updated systematic review and meta-analysis of randomized controlled ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2022.915463

The Role of Artificial Intelligence on Tumor Boards: Perspectives from Surgeons, Medical Oncologists and Radiation Oncologists

Valerio Nardone, Federica Marmorino, Marco Maria Germani, Natalia Cichowska-Cwalińska et al. • Current Oncology (2024)

The integration of multidisciplinary tumor boards (MTBs) is fundamental in delivering state-of-the-art cancer treatment, facilitating collaborative diagnosis and management by a diverse team of specialists. Despite the clear benefits in per...

DOAJ Open Access (DOAJ) DOI: 10.3390/curroncol31090369

Why did an effective Dutch complex psycho-social intervention for people with dementia not work in the German healthcare context? Lessons learnt from a process evaluation alongside a multicentre RCT

Sebastian Voigt-Radloff, Maud Graff, Myrra Vernooij-Dassen, Rainer Leonhart et al. • BMJ Open (2011)

Background The positive effects of the Dutch Community Occupational Therapy in Dementia programme on patients' daily functioning were not found in a multicentre randomised controlled trial (RCT) in Germany.Objectives To evaluate possible ef...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2011-000094

Local, collaborative, stepped, and personalized care management for older people with chronic diseases – results from the randomized controlled LoChro-trial

Gloria Metzner, Lukas Maximilian Horstmeier, Jürgen Bengel, Eva Maria Bitzer et al. • BMC Geriatrics (2023)

Abstract Background In the aging population of Western societies, an increasing number of older adults have multiple chronic diseases. As multifaceted health problems imply the involvement of several healthcare professionals, multimorbid ol...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-03797-2

Procedural Results and Long-Term Outcomes of Percutaneous Coronary Intervention for in-Stent Restenosis Chronic Total Occlusion Compared with de novo Chronic Total Occlusion

Tang G, Zheng N, Yang G, Li H et al. • International Journal of General Medicine (2021)

Guodong Tang, Naixin Zheng, Guojian Yang, Hui Li, Hu Ai, Ying Zhao, Fucheng Sun, Huiping Zhang Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences,...

DOAJ Open Access (DOAJ)

Associations between occupational performance and quality of life, well-being, and instrumental activities of daily living in older adults

Emi Miki, Risa Kawabata • Cadernos Brasileiros de Terapia Ocupacional (2020)

This study aimed to investigate the associations between occupational performance and quality of life, well-being, and instrumental activities of daily living in older Japanese adults by examining the correlations between the Canadian Occup...

DOAJ Open Access (DOAJ) DOI: 10.4322/2526-8910.ctoAO2096

HEART Camp Connect—Promoting adherence to exercise in adults with heart failure with preserved ejection fraction

Windy W. Alonso, Sara E. Bills, Scott W. Lundgren, Steven J. Keteyian et al. • ESC Heart Failure (2025)

Abstract Aims Most adults with stable heart failure are safe to exercise at a moderate intensity for 150 min/week. Regular participation in exercise may improve outcomes in adults with heart failure with preserved ejection fraction (HFpEF)....

DOAJ Open Access (DOAJ) DOI: 10.1002/ehf2.15341

Having More Daughters Independently Predicts Home Discharge in Stroke Patients Admitted to Inpatient Rehabilitation Ward

Shiau-Fu Hsieh, Kuo-Liong Chien, Chu-Hao Weng, Yi-Ping Chiang • International Journal of Gerontology (2017)

Background: The predictors for failure of home discharge after post-acute inpatient stroke rehabilitation need investigation. Methods: With this retrospective case-control study conducted in a stroke rehabilitation unit in one tertiary hosp...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijge.2017.07.005

Music therapy-induced changes in salivary cortisol level are predictive of cardiovascular mortality in patients under maintenance hemodialysis

Hou YC, Lin YJ, Lu KC, Chiang HS et al. • Therapeutics and Clinical Risk Management (2017)

Yi-Chou Hou,1 Yen-Ju Lin,2 Kuo-Cheng Lu,1 Han-Sun Chiang,3 Chia-Chi Chang,4 Li-King Yang1 1Department of Internal Medicine, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, 2Department of Nursing, Taipei Medical Univ...

DOAJ Open Access (DOAJ)