Academic Articles & Research Papers

Assessment of Quality of Life and Social Correlates among Drug Sensitive and Multidrug-resistant Tuberculosis Patients

Background: Tuberculosis (TB) has significant health, social, psychological, and economic impacts on patients. This study aimed to assess and compare quality of life (QOL) among multidrug-resistant (MDR) TB patients and drug-sensitive TB pa...

UNDERWEIGHT AND SLIMNESS AND THEIR RELATION TO DIETARY HABITS AND BLOOD PRESSURE AMONG SAUDI FEMALE STUDENTS IN TAIBAH UNIVERSITY

Background: Underweight is a term describing a human whose body weight is considered too low to be healthy. Underweight is associated with negative health consequences, such as nutritional deficiency, osteoporosis, and unfavorable pregnancy...

On mathematical modeling of fractional-order stochastic for tuberculosis transmission dynamics

Tuberculosis remains one of the most dangerous diseases globally and has affected many people in Sub-Saharan Africa. In this paper, a fractional stochastic model of tuberculosis disease was formulated and analyzed. The existence and uniquen...

Avoiding health technology assessment: a global survey of reasons for not using health technology assessment in decision making

INTRODUCTION: Despite the documented benefits of using health technology assessments (HTA) to inform resource allocation in health care systems, HTA remains underused, especially in low- and middle-income countries. A survey of global healt...

Innovative polymer-based electrochemical platform for detecting ESAT-6 in human blood for pulmonary tuberculosis diagnosis

Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), necessitates early diagnosis for effective patient care. Despite advancements in TB diagnostics, there remains an urgent need to discover innovative non-sputum-based m...

Oily start towards a medical biotechnology institute.

It is all about bringing scientific discovery in the medical biotechnology field to the bedside of patients \nwho need it, for which an institute is required to transfer the technology from the academic environment \ninto products for the m...

Epidemiology of Nosocomial Pneumonia

"Keep an open mind toward pneumonia. Our grandchildren will be interested and are likely to have as many differences of opinion.. as we have." William Osier, circa 1900 As Osier predicted nearly a century ago, controversies ^* * persist ove...

Mapping the Burden of Fungal Diseases in the United Arab Emirates

The United Arab Emirates has very little data on the incidence or prevalence of fungal diseases. Using total and underlying disease risk populations and likely affected proportions, we have modelled the burden of fungal disease for the firs...

Multiple bottlenecks constrain presentation of Mycobacterium tuberculosis antigens on MHC class I.

NON-INVASIVE INVESTIGATIONS IN HEROIN USERS AND NON-USERS-A CASE CONTROL STUDY

bjective: To compare heroin users with their age and gender matched relatives as regards non-invasive investigations like chest x-ray, electrocardiography (ECG) and 2D-echocardiography. Study Design: Case control study. Place and Duration o...

High helminthic co-infection in tuberculosis patients with undernutritional status in northeastern Ethiopia

Abstract Background Tuberculosis and parasitosis are the widely distributed diseases in Ethiopia with the leading cause of mortality and morbidity, respectively. There has been no information on the status of co-infections of tuberculosis a...

MOLECULAR BIOLOGY OF THE MYCOBACTERIA

The molecular biology of the mycobacteria is poised at the threshold of making major contributions to the understanding of the biochemistry and pathogenic mechanisms involved in mycobacterial infections.The application of molecular biology ...

The miRNA neuroinflammatory biomarkers in COVID-19 patients with different severity of illness

Introduction: The expression of specific miRNAs and their mRNA targets are changed in infectious disease. The aim of this study was to analyze the expression of pro-neuroinflammatory miRNAs, anti-neuroinflammatory miRNAs, and their mRNA tar...

Oxford Textbook of Public Health

SECTION 1: THE DEVELOPMENT OF THE DISCIPLINE OF PUBLIC HEALTH 1.1 The scope and concerns of public health 1.2 The history and development of public health in high-income countries 1.3 The history and development of public health in low- and...

MmpL Proteins in Physiology and Pathogenesis of M. tuberculosis

Mycobacterium tuberculosis (Mtb) remains an important human pathogen. The Mtb cell envelope is a critical bacterial structure that contributes to virulence and pathogenicity. Mycobacterial membrane protein large (MmpL) proteins export bulky...

Genome-wide association studies for the identification of cattle susceptible and resilient to paratuberculosis

Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne's disease or paratuberculosis (PTB), with important animal health and economic implications. There are no therapeutic strategies to control this disease, and vaccination with in...

Analysing interventions designed to reduce tuberculosis-related stigma: A scoping review.

Stigma is a critical barrier for TB care delivery; yet data on stigma reduction interventions is limited. This review maps the available literature on TB stigma reduction interventions, using the Health Stigma and Discrimination framework a...

Long-Acting Nanomedicine for Tuberculosis: A Mechanism-Informed Framework.

Resistance-gene minority variation and delayed microbiological response in rifampicin-resistant tuberculosis.

Explainable machine learning for predicting clinical outcomes in HIV/TB co-infection: a comparative retrospective study

Abstract Background HIV/TB co-infection presents substantial public-health challenges, showing greater treatment-failure and mortality rates than tuberculosis alone. Recent advances in machine learning (ML) provide a robust means of identif...