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Showing 20 of 132 academic articles

Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients

Supachai Sakkhachornphop, Sudarat Hadpech, Tanchanok Wisitponchai, Chansunee Panto et al. • Viruses (2018)

Certain proteins have demonstrated proficient human immunodeficiency virus (HIV-1) life cycle disturbance. Recently, the ankyrin repeat protein targeting the HIV-1 capsid, AnkGAG1D4, showed a negative effect on the viral assembly of the HIV...

DOAJ Open Access (DOAJ) DOI: 10.3390/v10110625

Evolution of the tripartite symbiosis between earthworms, Verminephrobacter and Flexibacter-like bacteria

Peter eMøller, Marie Braad Lund, Andreas eSchramm • Frontiers in Microbiology (2015)

Nephridial (excretory organ) symbionts are widespread in lumbricid earthworms and the complexity of the nephridial symbiont communities varies greatly between earthworm species. The two most common symbionts are the well-described Vermineph...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2015.00529

Botnet detection using graph-based feature clustering

Sudipta Chowdhury, Mojtaba Khanzadeh, Ravi Akula, Fangyan Zhang et al. • Journal of Big Data (2017)

Abstract Detecting botnets in a network is crucial because bots impact numerous areas such as cyber security, finance, health care, law enforcement, and more. Botnets are becoming more sophisticated and dangerous day-by-day, and most of the...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40537-017-0074-7

Analysis of factors affecting the length of stay of patients using clustering and association rules (Case study: Amir al-Momenin Hospital, Maragheh)

Mahdi Yousefi Nejad, Karim Farajian, Hossein Jaleb • مدیریت مهندسی و رایانش نرم (2025)

One of the major indicators in evaluating the performance of hospitals and their managers is the average length of stay of patients; given the importance of this indicator, the present study has examined the factors affecting the length of ...

DOAJ Open Access (DOAJ) DOI: 10.22091/jemsc.2025.11174.1195

Time dynamics of symptom progression in patients with acute pancreatitis: a Dynamic Time Warping analysis

Rui Han, Xiaoyu Deng, Hebing Liu, Yujie Duan et al. • Frontiers in Medicine (2025)

BackgroundAcute pancreatitis (AP) morbidity has been increasing in recent years. Patients with AP exhibit highly variable symptom patterns over time, posting challenges to traditional analytical methods. Dynamic Time Warping (DTW) effective...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2025.1703268

Identification of Specific IgE Antibodies and Asthma Control Interaction and Association Using Cluster Analysis in a Bulgarian Asthmatic Children Cohort

Snezhina Lazova, Tsvetelina Velikova, Stamatios Priftis, Guergana Petrova • Antibodies (2020)

(1) Background: Asthma is a complex heterogeneous disease that likely comprises several distinct disease phenotypes, where the clustering approach has been used to classify the heterogeneous asthma population into distinct phenotypes; (2) M...

DOAJ Open Access (DOAJ) DOI: 10.3390/antib9030031

Mapping Intellectual Structure of Health Literacy Area Based on Co-Word Analysis in Web of Science Database during the Years 1993-2017

Fatemeh Baji, Fereydoun Azadeh, Parastoo Parsaei-Mohammadi, Shoukat Parmah • مدیریت اطلاعات سلامت (2018)

Introduction: Creating an image of the conceptual structure of health literacy area, as well as the study of interdisciplinary and the relationship between its domains seems necessary. The present study examined the intellectual structure o...

DOAJ Open Access (DOAJ) DOI: 10.22122/him.v15i3.3577

Examining Rural and Urban Sentiment Difference in COVID-19–Related Topics on Twitter: Word Embedding–Based Retrospective Study

Yongtai Liu, Zhijun Yin, Congning Ni, Chao Yan et al. • Journal of Medical Internet Research (2023)

BackgroundBy the end of 2022, more than 100 million people were infected with COVID-19 in the United States, and the cumulative death rate in rural areas (383.5/100,000) was much higher than in urban areas (280.1/100,000). As the pandemic s...

DOAJ Open Access (DOAJ) DOI: 10.2196/42985

Growing functional modules from a seed protein via integration of protein interaction and gene expression data

Dimitrakopoulou Konstantina, Maraziotis Ioannis A, Bezerianos Anastasios • BMC Bioinformatics (2007)

Abstract Background Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the organization of PPI networks is the existence of dense...

DOAJ Open Access (DOAJ) DOI: 10.1186/1471-2105-8-408

Understanding Public Perceptions of Lung Cancer in China: Infodemiology Study of Baidu Index and Weibo Posts

Zongyuan Li, Jian Zhang, Yiming Fan, Nan Chen et al. • Journal of Medical Internet Research (2026)

Abstract BackgroundIn China, lung cancer remains a major public health concern and accounts for a substantial proportion of cancer-related deaths nationwide. However, limited research has examined public perceptions of lung canc...

DOAJ Open Access (DOAJ) DOI: 10.2196/85058

Mapping the Domain of Medical Informatics

Jan L. Talmon, Peter W. Moorman, Jan A. Kors, Martijn J. Schuemie • Methods of Information in Medicine (2008)

OBJECTIVES: The domain of medical informatics (MI) is not well defined. It covers a wide range of research topics. Our objective is to characterize the field of MI by means of the scientific literature in this domain. METHODS: We used title...

OPENALEX DOI: https://doi.org/10.3414/me0576

Sources of Information and Behavioral Patterns in Online Health Forums: Observational Study

Sudau, Fabian, Friede, Tim, Grabowski, Jens, Koschack, Janka et al. • Journal of Medical Internet Research (2014)

BackgroundIncreasing numbers of patients are raising their voice in online forums. This shift is welcome as an act of patient autonomy, reflected in the term “expert patient”. At the same time, there is considerable concern that patients ca...

DOAJ Open Access (DOAJ) DOI: 10.2196/jmir.2875

Toward an integrated approach for mental health and psychosocial support and peacebuilding in North-East Nigeria: programme description and preliminary outcomes from ‘Counselling on Wheels’

Sharli Paphitis, Fatima Akilu, Natasha Chilambo, Abiye Iruayenama et al. • BJPsych Open (2023)

Background Despite theoretical support for including mental health and psychosocial support (MHPSS) with peacebuilding, few programmes in conflict-affected regions fully integrate these approaches. Aims To describe and assess preliminary o...

DOAJ Open Access (DOAJ) DOI: 10.1192/bjo.2023.575

Evaluating Urban–Rural Disparity of Public Facilities Provision in Chengdu–Chongqing: An Equity Index Approach with Multi-Source Data

Xuan Liu, Youxin Qian, Guohui Zhou, Guangyu Xu et al. • Systems (2026)

Urban–rural public facility disparity is a systemic challenge that reflects dysfunctional feedback loops within and across social and technical subsystems. Traditional administrative-unit-based analyses cannot capture such systemic alignmen...

DOAJ Open Access (DOAJ) DOI: 10.3390/systems14080903

Clustering TV Viewing Behavior for Digital Twin Construction Using Television Viewing History Data

Daiki Mayumi, Hiroki Matsuda, Tetsuya Yokota, Taichi Sakakibara et al. • IEEE Access (2025)

This study presents the construction of the first digital twin utilizing non-identifiable television viewing history data. As the media landscape continues to evolve, understanding viewer behavior has become increasingly crucial. By simulat...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2025.3630660