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Efficacy of heel lifts versus calf muscle eccentric exercise for mid-portion Achilles tendinopathy (the HEALTHY trial): study protocol for a randomised trial

Chantel L. Rabusin, Hylton B. Menz, Jodie A. McClelland, Angela M. Evans et al. • Journal of Foot and Ankle Research (2019)

Abstract Background Mid-portion Achilles tendinopathy is a common musculoskeletal condition characterised by degeneration of the Achilles tendon, which causes pain and disability. Multiple non-surgical treatments have been advocated for thi...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13047-019-0325-2

Investigation the effects of economics – safety performance indices changes on average of lost work days (case study in the project refinery installation)

E ansari, Sh vosoghi • Salāmat-i kār-i Īrān (2016)

Background and aims: According to the International Labour Organization, 17% of fatal accidents occur in construction projects and development Workshop. While this number in Iran according to the Labor Department is 46%. In developing Asian...

DOAJ Open Access (DOAJ)

Cracking rare disorders: a new minimally invasive RNA-seq protocol

Laurenz De Cock, Erika D’haenens, Lies Vantomme, Lynn Backers et al. • npj Genomic Medicine (2025)

Abstract RNA sequencing (RNA-seq) has become key to complementing exome and genome sequencing for variant interpretation. We present a minimally invasive RNA-seq protocol using short-term cultured peripheral blood mononuclear cells (PBMCs) ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41525-025-00502-7

Hospitalisations for physical abuse in infants and children less than 5 years, 2013‒2021: a multinational cohort study using administrative data from five European countries

Catherine Quantin, Jonathan Cottenet, Colleen Chambers, Natasha Kennedy et al. • International Journal of Population Data Science (2025)

Objectives Child physical abuse (CPA) is a global public health problem associated with lifelong negative consequences, yet reliable epidemiologic data are lacking. We did a multinational cohort study to analyse trends in CPA hospitalisatio...

DOAJ Open Access (DOAJ) DOI: 10.23889/ijpds.v10i3.3028

Evaluation of clinical quality improvement interventions: feasibility of an integrated approach

Sandeep Reddy, Kevin Mc Namara, Mary Malakellis, Tim Denton et al. • Pilot and Feasibility Studies (2019)

Abstract Background Cardiovascular diseases (CVD) are the largest cause of death and disability in Australia. Australian national guidelines for the primary prevention of CVD recommend that all adults without CVD and aged 45 years or more a...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40814-018-0386-1

Obstetric complications in children with Attention Deficit/Hyperactivity Disorder and Learning Disability

Mamatha Bhat, Natalie Grizenko, Ben-Amor L, Ridha Joober • McGill Journal of Medicine (2020)

This study aims to determine whether children with ADHD and learning disabilities (LD) have a significant history of obstetrical complications when compared to children with ADHD but without LD. Methods: Sixty-four children aged 6 to 12 yea...

DOAJ Open Access (DOAJ) DOI: 10.26443/mjm.v8i2.502

Mathematics and Learning Disabilities

David C. Geary • Journal of Learning Disabilities (2004)

Between 5% and 8% of school-age children have some form of memory or cognitive deficit that interferes with their ability to learn concepts or procedures in one or more mathematical domains. A review of the arithmetical competencies of thes...

OPENALEX DOI: https://doi.org/10.1177/00222194040370010201

Spatiotemporal analysis of hospitalizations, mortality and access to intravenous thrombolysis for ischemic stroke in Southern Brazil

Samile Bonfim, Miyoko Massago, Vinicius Lopes Giacomin, Matheus Henrique Arruda Beltrame et al. • BMC Public Health (2026)

Abstract Background Globally, stroke is a leading cause of mortality and disability, affecting approximately 15 million people annually. This study aimed to analyze hospitalizations, deaths, and thrombolysis for ischemic stroke in Southern ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12889-026-27097-7

The worlds of disability and health technologies

Gerard Michael Goggin, Surona J. Visagie • Routledge eBooks (2024)

In this chapter, we discuss the dynamic area of technology in global health. Disability figures prominently, however, it is often framed in ways that leave people with disability excluded or positioned at the margins. This negative approach...

OPENALEX DOI: https://doi.org/10.4324/9781003228059-43

Structural dataset for the PPARγ V290M mutant

Ana C. Puhl, Paul Webb, Igor Polikarpov • Data in Brief (2016)

Loss-of-function mutation V290M in the ligand-binding domain of the peroxisome proliferator activated receptor γ (PPARγ) is associated with a ligand resistance syndrome (PLRS), characterized by partial lipodystrophy and severe insulin resis...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2016.03.082

A career in medical informatics

Mohammad Al‐Ubaydli • BMJ (2002)

Mohammad Al-Ubaydli explains how to have a career in medical informatics1 If you want to understand why I love technology, take a look at my hearing aid. Just before starting my house job, my nightmare scenario was of being deafened by the...

OPENALEX DOI: https://doi.org/10.1136/sbmj.0208279

A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis

Michael Barnett, Dongang Wang, Heidi Beadnall, Antje Bischof et al. • npj Digital Medicine (2023)

Abstract Modern management of MS targets No Evidence of Disease Activity (NEDA): no clinical relapses, no magnetic resonance imaging (MRI) disease activity and no disability worsening. While MRI is the principal tool available to neurologis...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41746-023-00940-6

Adaptation of the Stakeholders’ Walkability/Wheelability Audit in Neighborhoods (SWAN) Tool for Individuals With Diverse Disabilities: Protocol for a Mixed Methods Study

Atiya Mahmood, Farinaz Rikhtehgaran, Rojan Nasiri, Niloofar Hedayati et al. • JMIR Research Protocols (2025)

BackgroundThe prevalence of sensory, cognitive, and mobility disabilities in Canada underscores the need to address environmental barriers. This study adapts and validates the Stakeholders’ Walkability/Wheelability Audit in Neighborhoods (S...

DOAJ Open Access (DOAJ) DOI: 10.2196/60553

Digital Exclusion and Cognitive Function in Elderly Populations in Developing Countries: Insights Derived From 2 Longitudinal Cohort Studies

Sainan Duan, Dongxu Chen, Jinping Wang, Mohammed Sharooq Paramboor et al. • Journal of Medical Internet Research (2024)

BackgroundCognition disorders not only lead to adverse health consequences but also contribute to a range of socioeconomic challenges and diminished capacity for performing routine daily activities. In the digital era, understanding the imp...

DOAJ Open Access (DOAJ) DOI: 10.2196/56636

Memantine for Refractory Obsessive-Compulsive Disorder: Protocol for a Pragmatic, Double-blind, Randomized, Parallel-Group, Placebo-Controlled, Monocenter Trial

Annalisa Maraone, Alessandro Trebbastoni, Antonella Di Vita, Fabrizia D'Antonio et al. • JMIR Research Protocols (2023)

BackgroundObsessive-compulsive disorder (OCD) is a psychiatric syndrome characterized by unwanted and repetitive thoughts and repeated ritualistic compulsions for decreasing distress. Symptoms can cause severe distress and functional impair...

DOAJ Open Access (DOAJ) DOI: 10.2196/39223

Specificity Protein 1: A Protein With a Two-Sided Role in Ischemic Stroke

Qinyang Yu, Qinyang Yu, Wangyang Liu, Wangyang Liu et al. • Frontiers in Cellular Neuroscience (2021)

Stroke is one of the leading causes of death and disability worldwide. However, there is a lack of effective medications to speed up the recovery process. Ischemic stroke, as the result of cerebral infarction or cerebral artery narrowing, i...

DOAJ Open Access (DOAJ) DOI: 10.3389/fncel.2021.757670

Emerging Role of Ferroptosis in the Pathogenesis of Ischemic Stroke: A New Therapeutic Target?

Zhong-Qi Bu, Hai-Yang Yu, Jue Wang, Xin He et al. • ASN Neuro (2021)

Ischemic stroke is one of the main causes of high morbidity, mortality, and disability worldwide; however, the treatment methods are limited and do not always achieve satisfactory results. The pathogenesis of ischemic stroke is complex, def...

DOAJ Open Access (DOAJ) DOI: 10.1177/17590914211037505

SIRT1 and miR-34a as Potential Plasma Biomarkers in the Acute Phase of Ischemic Stroke

Mitra Ansari, Moslem Esmati, Seyed khalil Rashidi, Shahram Rafie et al. • International Journal of Molecular and Cellular Medicine (2025)

Stroke is the major cause of disability and mortality worldwide. Identification of molecular biomarkers in the early hours after stroke is important in terms of both diagnostic and therapeutic applications. miR-34a, a highly expressed miRNA...

DOAJ Open Access (DOAJ)

Expanding the genetic spectrum of hereditary motor sensory neuropathies in Pakistan

Asif Naveed Ahmed, Lettie E. Rawlins, Niamat Khan, Zakir Jan et al. • BMC Neurology (2024)

Abstract Background Hereditary motor and sensory neuropathy (HMSN) refers to a group of inherited progressive peripheral neuropathies characterized by reduced nerve conduction velocity with chronic segmental demyelination and/or axonal dege...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12883-024-03882-y

Burden of five healthcare associated infections in Australia

M. J. Lydeamore, B. G. Mitchell, T. Bucknall, A. C. Cheng et al. • Antimicrobial Resistance and Infection Control (2022)

Abstract Background Healthcare associated infections are of significant burden in Australia and globally. Previous estimates in Australia have relied on single-site studies, or combinations thereof, which have suggested the burden of these ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13756-022-01109-8