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Showing 20 of 125 academic articles

The RootChip: An Integrated Microfluidic Chip for Plant Science

Guido Großmann, Woei‐Jiun Guo, David W. Ehrhardt, Wolf Bernd Frommer et al. • The Plant Cell (2011)

Studying development and physiology of growing roots is challenging due to limitations regarding cellular and subcellular analysis under controlled environmental conditions. We describe a microfluidic chip platform, called RootChip, that in...

OPENALEX cc-by DOI: https://doi.org/10.1105/tpc.111.092577 PMC: 3269862

Metabolites extracted from browntop millet (Urochloa ramosa (L.) T.Q. Nguyen) mitigated the proliferation of breast- and colorectal carcinoma cells in vitro and retarded the EAC tumors in vivo by binding to oncogenic proteins

Mahadevaswamy G. Kuruburu, Venugopal R. Bovilla, Rimshia Naaz, Zonunsiami Leihang et al. • Frontiers in Pharmacology (2026)

Epidemiological studies have demonstrated an inverse correlation between millet-based diets and incidence of cancers of colon and rectum. These findings highlight the potential of millets as functional foods for effective management of canc...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2026.1805287

Effects of Dynamic Neuromuscular Stabilization on Lower Limb Muscle Activity, Pain, and Disability in Individuals with Chronic Low Back Pain: A Randomized Controlled Trial

Farhad Rezazadeh, Shirin Aali, Fariborz Imani, Hamed Sheikhalizadeh et al. • Medicina (2025)

Background and Objectives: Chronic low back pain (CLBP) is associated with altered neuromuscular control. Dynamic Neuromuscular Stabilization (DNS) targets core–limb coordination; however, its specific impact on lower-limb electromyographic...

DOAJ Open Access (DOAJ) DOI: 10.3390/medicina61111961

The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate

Esteve Pilar, Lopez-Rios Javier, Ruiz Jose, Bovolenta Paola • Neural Development (2008)

Abstract Background Secreted frizzled related proteins (SFRPs) are multifunctional modulators of Wnt and BMP (Bone Morphogenetic Protein) signalling necessary for the development of most organs and the homeostasis of different adult tissues...

DOAJ Open Access (DOAJ) DOI: 10.1186/1749-8104-3-19

Association of inflammation and cognition in the elderly: A systematic review and meta-analysis

Sofia Leonardo, Felipe Fregni • Frontiers in Aging Neuroscience (2023)

BackgroundThe development of mild cognitive impairment (MCI) and Alzheimer’s disease (AD) may be associated with an inflammatory process. Inflammatory cytokines may be a surrogate for systemic inflammation leading to worsening neurological ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnagi.2023.1069439

Effect of probiotics on cognitive function and cardiovascular risk factors in mild cognitive impairment and Alzheimer’s disease: an umbrella meta-analysis

Bin Xiao, Lina Fu, Zhe Yang, Guran Yu • Journal of Health, Population and Nutrition (2025)

Abstract Background This umbrella meta-analysis evaluates the effects of probiotics on cognitive function and metabolic health in Alzheimer’s disease (AD) and mild cognitive impairment (MCI) by synthesizing findings from meta-analyses of ra...

DOAJ Open Access (DOAJ) DOI: 10.1186/s41043-025-00816-3

The effects of anodal transcranial direct current stimulation on psychological factors in athletes: a systematic review and meta-analysis

Mahdi Mollazadeh, Sara Ramezanpour • BMC Psychology (2026)

Abstract Objective Transcranial direct current stimulation (tDCS) is a safe, non-invasive neuromodulation method that delivers a low-intensity, constant direct current through electrodes positioned on the scalp. Therefore, the purpose of th...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40359-026-05000-8

Melatonin: dual players mitigating drought-induced stress in tomatoes via modulation of phytohormones and antioxidant signaling cascades

Shifa Shaffique, Anis Ali Shah, Sang-Mo Kang, Md. Injamum-Ul-Hoque et al. • BMC Plant Biology (2024)

Abstract Drought stress significantly retards the plant production. Melatonin is a vital hormone, signaling molecule, and bio-regulator of diverse physiological growth and development processes. Its role in boosting agronomic traits under d...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12870-024-05752-8

RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis.

Brianna Dufek, Daniel T Meehan, Duane Delimont, Kevin Wilhelm et al. • PLoS ONE (2020)

Previous work demonstrates that the hearing loss in Alport mice is caused by defects in the stria vascularis. As the animals age, progressive thickening of strial capillary basement membranes (SCBMs) occurs associated with elevated levels o...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0237907

CircHIPK3 regulates cardiac fibroblast proliferation, migration and phenotypic switching through the miR-152-3p/TGF-β2 axis under hypoxia

Weiwei Liu, Yan Wang, Zhimei Qiu, Ranzun Zhao et al. • PeerJ (2020)

Background The occurrence of pathological cardiac fibrosis is attributed to tissue hypoxia. Circular RNAs play significant regulatory roles in multiple cardiovascular diseases and are involved in the regulation of physiological and pathophy...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.9796

Concept of Sporadic E Monitoring Using Space-Based Low Power Multiple Beacon-Systems

Jurgen Vanhamel, Marc Berwaerts, Stefano Speretta, Sevket Uludag • Atmosphere (2024)

Current monitoring systems to detect sporadic E use ground-based setups, ionosondes, and the network of GNSS satellites in order to assess the phenomenon of sporadic E. This paper aims to monitor sporadic E using a miniature space-based pla...

DOAJ Open Access (DOAJ) DOI: 10.3390/atmos15111306

Effet de l'illumination proche infra-rouge intracérébrale chez des primates MPTP

Fannie Darlot, Cécile Moro, Napoléon Torres‑Martinez, Claude Chabrol et al. • Revue de Primatologie (2015)

La maladie de Parkinson (MP) est une maladie neurodégénérative chronique affectant le système dopaminergique et se traduisant par une perte des neurones dopaminergiques (DA) de la substance noire compacta (SNc) et des faisceaux nigro-striés...

DOAJ Open Access (DOAJ) DOI: 10.4000/primatologie.2073

Lactobacillus brevis 23017 Relieves Mercury Toxicity in the Colon by Modulation of Oxidative Stress and Inflammation Through the Interplay of MAPK and NF-κB Signaling Cascades

Xinpeng Jiang, Shanshan Gu, Di Liu, Lili Zhao et al. • Frontiers in Microbiology (2018)

Aims:Lactobacillus strains have protective effects against heavy metals while relieving oxidative stress and modulating the immune response. Mechanisms that ameliorate heavy metal toxicity and the relationship between probiotics and gut bar...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2018.02425

Fumaric acid regulates morphine tolerance in bone cancer pain through spinal MrgC receptor modulation

Sijie Liu, Minghao Tang, Jing Zhao, Lulu Zhang et al. • Pakistan Journal of Pharmaceutical Sciences (2026)

Background: Bone cancer pain (BCP) represents a debilitating complication that profoundly impacts patient quality of life and predisposes to psychological comorbidities, including depression and anxiety. Objectives: To investigate the effec...

DOAJ Open Access (DOAJ) DOI: 10.36721/PJPS.2026.39.8.233.1

Modulation Instability and Abundant Exact Solitons to the Fractional Mathematical Physics Model Through Two Distinct Methods

Abdulaziz Khalid Alsharidi, Ahmet Bekir • Axioms (2025)

The paper consists of various types of wave solutions for the truncated M-fractional Bateman–Burgers equation, a significant mathematical physics equation. This model describes the nonlinear waves and solitons in different physical fields s...

DOAJ Open Access (DOAJ) DOI: 10.3390/axioms14080617

Controlled Plasmonic Coupling in Silver Nanoplate Dimers for Enhanced Plasmonic Sensing

Lucrezia Catanzaro, Marcello Condorelli, Mario Pulvirenti, Luisa D’urso et al. • Nanomaterials (2026)

Noble metal nanostructures provide versatile platforms for light manipulation through localized surface plasmon resonances (LSPRs). Among them, triangular silver nanoplates (AgNPTs) exhibit strong field-enhancement and spectral tunability, ...

DOAJ Open Access (DOAJ) DOI: 10.3390/nano16080486

Generation of Subdiffraction Optical Needles by Simultaneously Generating and Focusing Azimuthally Polarized Vortex Beams through Pancharatnam–Berry Metalenses

Zhe Shen, Shijie Huang • Nanomaterials (2022)

Needle beams have received widespread attention due to their unique characteristics of high intensity, small focal size, and extended depth of focus (DOF). Here, a single–layer all–dielectric metalens based on Pancharatnam–Berry (PB) was us...

DOAJ Open Access (DOAJ) DOI: 10.3390/nano12224074

High performance thin-film lithium niobate modulator on a silicon substrate using periodic capacitively loaded traveling-wave electrode

Gengxin Chen, Kaixuan Chen, Ranfeng Gan, Ziliang Ruan et al. • APL Photonics (2022)

Thin-film lithium niobate (TFLN) based traveling-wave modulators maintain simultaneously excellent performances, including large modulation bandwidth, high extinction ratio, low optical loss, and high modulation efficiency. Nevertheless, th...

DOAJ Open Access (DOAJ) DOI: 10.1063/5.0077232