Academic Articles & Research Papers

Development of WEFIT Screening Tool for Assessing Pre-exercise Fitness Level for Older Adults in Peninsular Malaysia

Background: Pre-exercise screening is important to identify the fitness level of older adults prior to performing exercise. This study aimed to develop a screening tool for identifying older adults with poor physical fitness prior to exerci...

Cost Effectiveness Modelling for Health Technology Assessment

Neuropsychological Health Technologies

The article reveals the problem of neuropsychological technologies for maintaining, strengthening and developing human health from early to adulthood as a set of corrective and developmental measures to ensure the relationship of an optimal...

Further validation of the Chinese short Warwick Edinburgh mental wellbeing scale in the adult population of Macau: an application of classic test theory and item response theory

BackgroundThis study aims to validate the Chinese version of the Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS) by employing both Classical Test Theory (CTT) and Item Response Theory (IRT) approaches.MethodsData were gathered thr...

Design and evaluation guidelines for mental health technologies

It is increasingly recognised that technology has the potential to significantly improve access, engagement, effectiveness and affordability of treatment for mental health problems. The development of such technology has recently become the...

Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells

Abstract Semaphorin-3A (SEMA3A) functions as a chemorepulsive signal during development and can affect T cells by altering their filamentous actin (F-actin) cytoskeleton. The exact extent of these effects on tumour-specific T cells are not ...

Altered Red Blood Cell Fatty Acid and Serum Adipokine Profiles in Subjects with Obesity

Background: Adipokines, as well as the fatty acid profile of red blood cell (RBC) membranes, are known to play important roles in the development and progression of metabolic complications induced by obesity. Thus, the objective of this stu...

Persuasive Health Technology

As explained in Chapter 2 , behaviour change is important to improve health and well-being. Behaviour change techniques can be applied in the design of eHealth technology to support users in reaching their goals. Persuasive technology can p...

THE VALUES FOSTERED BY HEALTH TECHNOLOGY

The values and knowledge claims circulating in the health policy arena regarding health technologies (i.e., devices, diagnostics) are complex and often include arguments...

International diffusion of new health technologies: A ten-country analysis of six health technologies

OBJECTIVES: The objective of this study was to examine and explain the differential international diffusion of six health innovations. METHODS: A retrospective diffusion study was undertaken of sildenafil, cyclooxygenase-II (COX II) inhibit...

Clinical and cost-effectiveness of a standardised diagnostic assessment for children and adolescents with emotional difficulties: the STADIA multi-centre RCT

Background Emotional disorders are common in children and young people and can significantly impair their quality of life. Evidence-based treatments require a timely and appropriate diagnosis. The utility of standardised diagnostic assessme...

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

Respiratory disease: A bovine model for respiratory syncytial virus vaccines Researchers have produced a vaccine that protects against bovine respiratory syncytial virus (bRSV) in calves, with implications for humans. An international team ...

Effects of an infant formula containing a whey protein concentrate on feeding tolerance and markers of intestinal immune defense in Chinese infants

Abstract Background Human milk (HM) bioactive components can have immune modulatory functions, impact the gut microbiome, and may result in functional benefits when added to infant formula (IF). In this single-arm, prospective, intervention...

The Impact of Bio-Based Fertilizer Integration Into Conventional Grassland Fertilization Programmes on Soil Bacterial, Fungal, and Nematode Communities

Phosphorus (P) is an essential plant macro-nutrient applied to soil in agriculture, mainly sourced from non-renewable mined phosphate-rock, of which readily accessible reserves are currently under pressure, while global food demand continue...

Health Technology Assessment

This article describes health technology assessment (HTA) as an evaluation tool that applies systematic methods of inquiry to the generation and use of health technologies and new products. The focus of this article is on the contributions ...

Technology Assessment and the Sociopolitics of Health Technologies

In a growing number of countries, health technology assessment (HTA) has come to be seen as a vital component in policy making. Even though the assessment of the social, political, and ethical aspects of health technology is listed as one o...

Medical Informatics Is Interdisciplinary avant la Lettre

OBJECTIVE: To discuss the elements of interdisciplinary research and to analyze its contribution to (bio)medical informatics. METHOD: Commenting on 'Informatics and Medicine - From Molecules to Populations' from K. A. Kuhn et al. in this is...

Education in Medical Informatics in the Federal Republic of Germany))

The paper deals with the present situation of education at the academic level in Medical Informatics (or Medical Information Science, Electronic Data Processing applied to medicine and the health care service etc.) in the Federal Republic o...

Assessing Acceptance and Intention to Use of Home Telemonitoring Among Patients with Liver Cirrhosis: Development and Initial Psychometric Validation of a TAM-Based Questionnaire

Background/Objectives: Liver cirrhosis (LC) is a major cause of morbidity and mortality requiring continuous monitoring and early recognition of clinical deterioration. Home telemonitoring is increasingly considered a supportive strategy fo...

Machine learning framework for early identification of high-spending Crohn’s disease patients using administrative claims

Objectives To develop and evaluate a machine learning (ML) model that predicts Crohn’s disease (CD) patients responsible for the top quartile of healthcare spending.Methods De-identified commercial claims (2016–2018) from ~267 000 continuou...