Academic Articles & Research Papers

Lactate-driven metabolic-epigenetic reprogramming in breast cancer: immune evasion and therapeutic resistance.

Parallel transcriptome adaptation during recent evolution of the Drosophila testis.

Gut microbiome maturation in early childhood interacts with host genetics to predict type 1 diabetes risk.

The Enigma of Finnish and Sardinian Type 1 Diabetes Incidence: Where Population History Meets Genetics.

Molecular Genetics and Reproductive Genomic Medicine in Cleft Lip and Palate: Current Evidence, Preimplantation Testing, and Clinical Translation-A Narrative Review.

GERBase: an online tool for high-resolution HLA allele and haplotype frequencies and linkage disequilibrium analysis in a Brazilian population.

Genomic sequencing technologies for rare disease in mainstream healthcare: the current state of implementation.

Abstracts from the 58(th) European Society of Human Genetics (ESHG) Conference: Hybrid Posters.

The spread of genomics.

Kinship estimation bias carries over to heritability estimation bias using variance components.

Automated wound care by employing a reliable U-Net architecture combined with ResNet feature encoders for monitoring chronic wounds

Quality of life is greatly affected by chronic wounds. It requires more intensive care than acute wounds. Schedule follow-up appointments with their doctor to track healing. Good wound treatment promotes healing and fewer problems. Wound ca...

A Rare Big Chinese Family With Thrombocytopenia 2: A Case Report and Literature Review

Thrombocytopenia 2 (THC2) is one of the most prevalent forms of inherited thrombocytopenia. It is caused by a heterogeneous group of ANKRD26 gene mutation and shows a heterogeneous clinical and laboratory characteristics. We present a big C...

Heat Stress in Livestock: Impacts and Ameliorative Strategies—a Review

               Heat stress is one of the most important climatic conditions which adversely affects agricultural and livestock production worldwide. High ambient temperature with direct and indirect solar radiation, wind speed and relative ...

Breast Cancer and miR-SNPs: The Importance of miR Germ-Line Genetics

Recent studies in cancer diagnostics have identified microRNAs (miRNAs) as promising cancer biomarkers. Single nucleotide polymorphisms (SNPs) in miRNA binding sites, seed regions, and coding sequences can help predict breast cancer risk, a...

Progressive suppression of regulated cell death defines terminal macrophage states in liver cirrhosis

Background Macrophages are central regulators of liver immunity and fibrosis; Recent single-cell studies have characterized macrophage heterogeneity in cirrhosis; however, how regulated cell death programs shape their functional transitions...

Post-Fire Abundance Trajectories of Bird Species and Functional Groups Within an Atlantic–Mediterranean Ecotone

The Atlantic–Mediterranean ecotone of northwestern Iberia is one of the most fire-prone regions in Europe, yet post-fire avian dynamics there remain poorly documented. To characterise short- to mid-term post-fire avian trajectories in this ...

Identification and Functional Assessment of the First Placental Adhesin of Treponema pallidum That May Play Critical Role in Congenital Syphilis

Syphilis is a global, re-emerging sexually transmitted infection and congenital syphilis remains a major cause of adverse pregnancy outcomes due to bacterial infection in developing nations with a high rate of fetus loss. The molecular mech...

Generation of human induced pluripotent stem cell line MHHi040-A from a female Fabry disease patient carrying c.644A>G missense mutation

Fabry disease (FD) is an X-linked, monogenic lysosomal storage disorder, caused by mutations in the GLA gene. GLA encodes the lysosomal hydrolase alpha-galactosidase A and enzyme deficiency leads to accumulation of its substrate globotriaos...

Synergistic Effects of Resveratrol and Temozolomide Against Glioblastoma Cells: Underlying Mechanism and Therapeutic Implications

Yusi Liu, Xue Song, Moli Wu, Jiao Wu, Jia Liu Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, People’s Republic of ChinaCorre...

Editorial: The neurogenetics of brain wiring