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Sex- and age-specific effects of fat distribution on bone mineral density

Xiao Lin, Jun-Jie Yang, Bei Huang, Peng-Xin Wang et al. • Experimental Gerontology (2026)

Background: BMI cannot distinguish fat distribution and may mask the true effects of different fat depots on bone mineral density (BMD). To investigate sex- and age-specific associations between fat distribution and BMD and its mediating ro...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2026.113301

Correlation between sarcopenia and changes in oligodendrocyte lineage cells in the brains of Alzheimer's disease model mice

Lin-lin Yao, Xiao-ting Ma, Fang-bo Li, Lin-yi Zheng et al. • Experimental Gerontology (2026)

Background: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by cognitive dysfunction. The discovery and identification of non-cognitive symptoms in the preclinical stage hold promise for early diagnosis and ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2026.113057

Effectiveness of music-based interventions in acute care settings for people living with dementia to reduce anxiety and enhance the care experience: A systematic review.

Victoria McArthur, Susan Everington, Martyn Patel • Archives of Gerontology and Geriatrics Plus (2024)

Introduction: Dementia is a global health priority, with an increasing percentage of overall hospital bed days occupied by people with dementia (PWD). This combined with increased demand and availability of complex scanning means that there...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2024.100087

Advances in the Development of PET Ligands Targeting Histone Deacetylases for the Assessment of Neurodegenerative Diseases

Tetsuro Tago, Jun Toyohara • Molecules (2018)

Epigenetic alterations of gene expression have emerged as a key factor in several neurodegenerative diseases. In particular, inhibitors targeting histone deacetylases (HDACs), which are enzymes responsible for deacetylation of histones and ...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules23020300

Correlation between frailty and reduction in cortical thickness in patients with chronic obstructive pulmonary disease

Ayumi Fukatsu-Chikumoto, Tsunahiko Hirano, Shun Takahashi, Takuya Ishida et al. • Scientific Reports (2024)

Abstract Physical inactivity and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD) can lead to frailty and poor prognoses. However, little is known regarding the association between frailty and the human bra...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-53933-0

Soft x-ray high-harmonic generation in an anti-resonant hollow core fiber driven by a 3 μm ultrafast laser

D. Morrill, W. Hettel, D. Carlson, B. Shearer et al. • APL Photonics (2025)

High-harmonic upconversion driven by a mid-infrared femtosecond laser can generate coherent soft x-ray beams in a tabletop-scale setup. Here, we report on a compact ytterbium-pumped optical parametric chirped pulse amplifier (OPCPA) laser s...

DOAJ Open Access (DOAJ) DOI: 10.1063/5.0292771

Fast Timing Techniques in FLIM Applications

Liisa M. Hirvonen, Klaus Suhling • Frontiers in Physics (2020)

Fluorescence lifetime imaging (FLIM) is increasingly used in many scientific disciplines, including biological and medical research, materials science and chemistry. The fluorescence label is not only used to indicate its location, but also...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphy.2020.00161

Twins‐like nanodrugs synchronously transport in blood and coalesce inside tumors for sensitive ultrasound imaging and triggerable penetrative drug delivery

Yujun Cai, Gengjia Chen, Minzhao Lin, Bo Li et al. • Aggregate (2024)

Abstract Nanodrugs capable of aggregating in the tumor microenvironment (TME) have demonstrated great efficiency in improving the therapeutic outcome. Among various approaches, the strategy utilizing electrostatic interaction as a driving f...

DOAJ Open Access (DOAJ) DOI: 10.1002/agt2.476

Nanotechnology’s frontier in combatting infectious and inflammatory diseases: prevention and treatment

Yujing Huang, Xiaohan Guo, Yi Wu, Xingyu Chen et al. • Signal Transduction and Targeted Therapy (2024)

Abstract Inflammation-associated diseases encompass a range of infectious diseases and non-infectious inflammatory diseases, which continuously pose one of the most serious threats to human health, attributed to factors such as the emergenc...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41392-024-01745-z

Ultrasound-Sensitive Liposomes for Triggered Macromolecular Drug Delivery: Formulation and In Vitro Characterization

Maria B. C. de Matos, Roel Deckers, Benjamin van Elburg, Guillaume Lajoinie et al. • Frontiers in Pharmacology (2019)

Mistletoe lectin-1 (ML1) is a nature-derived macromolecular cytotoxin that potently induces apoptosis in target cells. Non-specific cytotoxicity to normal cells is one of the major risks in its clinical application, and we therefore propose...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2019.01463

Proteoliposomes – a system to study membrane proteins under buffer gradients by cryo-EM

Sejwal Kushal, Chami Mohamed, Baumgartner Paul, Kowal Julia et al. • Nanotechnology Reviews (2017)

Membrane proteins are vital to life and major therapeutic targets. Yet, understanding how they function is limited by a lack of structural information. In biological cells, membrane proteins reside in lipidic membranes and typically experie...

DOAJ Open Access (DOAJ) DOI: 10.1515/ntrev-2016-0081

Potential Applications of Nanotechnology for the Diagnosis and Treatment of Pancreatic Cancer

Joshua eMcCarroll, Joshua eMcCarroll, Joann eTeo, Joann eTeo et al. • Frontiers in Physiology (2014)

Despite improvements in our understanding of pancreatic cancer and the emerging concept of personalized medicine for the treatment of this disease, it is still the fourth most common cause of cancer death in the western world. It is establi...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphys.2014.00002

High-speed nonlinear focus-induced photoresponse in amorphous silicon photodetectors for ultrasensitive 3D imaging applications

Andreas Bablich, Maurice Müller, Paul Kienitz, Rainer Bornemann et al. • Scientific Reports (2022)

Abstract A large and growing number of applications benefit from simple, fast and highly sensitive 3D imaging sensors. The Focus-Induced Photoresponse (FIP) can achieve 3D sensing functionalities by simply evaluating the irradiance dependen...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-022-14330-7

Nanotechnology: The future medicine

Rajiv Saini, Santosh Saini, Sugandha Sharma • Journal of Cutaneous and Aesthetic Surgery (2010)

Nanotechnology is an exciting new area in science, with many possible applications in medicine. This article seeks to outline the role of different areas such as diagnosis of diseases, drug delivery, imaging, and so on....

OPENALEX Open Access DOI: https://doi.org/10.4103/0974-2077.63301 PMC: 2890134

Seeking the Unseen: A Multimodal Non-Invasive Investigation of a Post-Byzantine Overpainted Icon

Nikoleta V. Nikolaidou, Anastasios Asvestas, Agathi Anthoula Kaminari, Theodoros Panou et al. • Heritage (2025)

Religious panel paintings (icons) play a pivotal role in the rituals of the Eastern Orthodox Christian Church. However, their continuous use often results in physical degradation, prompting remedial interventions. Quite commonly, alteration...

DOAJ Open Access (DOAJ) DOI: 10.3390/heritage8090377

Physical Characterization of Early Galaxies in the Webb’s First Deep Field SMACS J0723.3-7327

T. Morishita, M. Stiavelli • The Astrophysical Journal Letters (2023)

This paper highlights initial photometric analyses of JWST NIRCam imaging data in the sightline of SMACS0723, aiming to identify galaxies at redshift z > 7. By applying a conservative Lyman-break selection followed by photometric-redshift a...

DOAJ Open Access (DOAJ) DOI: 10.3847/2041-8213/acbf50

Searching for galaxy cluster-scale strong lenses from the DESI legacy imaging surveys

Zhejian Zhang, Nan Li, Shude Mao, Hu Zou et al. • Frontiers in Astronomy and Space Sciences (2026)

IntroductionGalaxy cluster-scale strong gravitational lensing systems are rare yet valuable tools for investigating dark matter and dark energy, as well as providing the opportunity to study the distant universe at flux levels and spatial r...

DOAJ Open Access (DOAJ) DOI: 10.3389/fspas.2026.1744079