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Roles of Rap1 signaling in tumor cell migration and invasion

Yi-Lei Zhang, Ruo-Chen Wang, Ken Cheng, Brian Z. Ring et al. • Cancer Biology & Medicine (2017)

Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization. Th...

DOAJ Open Access (DOAJ) DOI: 10.20892/j.issn.2095-3941.2016.0086

In vivo topology converts competition for cell-matrix adhesion into directional migration

Fernanda Bajanca, Nadège Gouignard, Charlotte Colle, Maddy Parsons et al. • Nature Communications (2019)

Migrating cells encounter multiple signals such as extracellular matrix (ECM) and chemokinetic factors but how these integrate in vivo is unclear. Here, the authors report that overall control of cell-ECM adhesion by Sema3A and Sdf1 can be ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-019-09548-5

CircHIPK3 regulates cardiac fibroblast proliferation, migration and phenotypic switching through the miR-152-3p/TGF-β2 axis under hypoxia

Weiwei Liu, Yan Wang, Zhimei Qiu, Ranzun Zhao et al. • PeerJ (2020)

Background The occurrence of pathological cardiac fibrosis is attributed to tissue hypoxia. Circular RNAs play significant regulatory roles in multiple cardiovascular diseases and are involved in the regulation of physiological and pathophy...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.9796

Impacts of land-use changes and landholding fragmentation on crop water demand and drought in Wadi El-Farigh, New Delta project, Egypt

Mohamed M. Elsharkawy, Mohsen Nabil, Eslam Farg, Sayed M. Arafat • Egyptian Journal of Remote Sensing and Space Sciences (2022)

Despite Egypt’s limited water resources, more lands in the western desert of the Nile Delta are currently being reclaimed to increase the agricultural area to feed its fast-growing population and provide jobs for new generations. These recl...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ejrs.2022.08.002

The effect of chili pepper-Chinese chives intercropping on rhizosphere microorganisms and root-stem endophytes

Nan Sun, Nan Sun, Yuxin Wang, Yuxin Wang et al. • Frontiers in Microbiology (2025)

IntroductionThis study adopted the intercropping pattern opepper (Capsicum annuum L.) and Chinese chives (Allium tuberosum), combined with high-throughput sequencing and microbial network analysis, to systematically reveal the mechanisms of...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2025.1716326

Angiogenesis as a Survival Mechanism in Heartworm Disease: The Role of Fructose-Bisphosphate Aldolase and Actin from <i>Dirofilaria immitis</i> in an In Vitro Endothelial Model

Manuel Collado-Cuadrado, Claudia Alarcón-Torrecillas, Alfonso Balmori-de la Puente, Iván Rodríguez-Escolar et al. • Animals (2024)

Heartworm disease, caused by Dirofilaria immitis, is a vector-borne zoonotic disease, (mainly affecting canids and felids) causing chronic vascular and pulmonary pathology in its early stages, which worsens with parasite load and/or death o...

DOAJ Open Access (DOAJ) DOI: 10.3390/ani14233371

Impact of internal remittance on households' use of bank services: evidence from Vietnam

Thu Thi Hoai Nguyen, Hung Manh Le, Le Quoc Hoi, Hang Thu Pham • Journal of Economics Finance and Administrative Science (2022)

Purpose – This study estimates impact of remittances from internal migration on households' use of bank services in Vietnam. Design/methodology/approach – This study uses data from the Vietnam Household Living Standards Survey and the two-s...

DOAJ Open Access (DOAJ) DOI: 10.1108/JEFAS-05-2021-0074

Implications of climate change on freshwater ecosystems and their biodiversity

Divya Nimma, Okram Ricky Devi, Bibek Laishram, Janjhyam Venkata Naga Ramesh et al. • Desalination and Water Treatment (2025)

Global warming is a phenomenon whereby the planet's exposure to the sun's radiation worsens from the high emission of gasses believed to trap heat within the atmosphere. Carbon dioxide (CO2) is the leading greenhouse gas majorly responsible...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dwt.2024.100889

Reconstructing lost memories: Social memory as a foundation for disaster mitigation in Pandai Sikek

Handrian Ginting Jonson, Afrida Afrida, Zulkifli Addina, Subhiati Nur et al. • E3S Web of Conferences (2025)

This study examines the 2024 flash flood in Pandai Sikek, West Sumatra, through the lens of disaster anthropology and social memory. Based on preliminary research and one week of ethnographic fieldwork, the research reveals that while extre...

DOAJ Open Access (DOAJ) DOI: 10.1051/e3sconf/202567702011

Enhanced Photocatalytic Degradation Activity of BiFeO3 Microspheres by Decoration with g-C3N4 Nanoparticles

Lijing Di, Hua Yang, Tao Xian, Xiujuan Chen • Materials Research (2018)

In this work, the g-C3N4 nanoparticles decorated BiFeO3 microspheres composites (g-C3N4/BiFeO3) were successfully synthesized by hydrothermal treatment of g-C3N4 nanoparticles together with BiFeO3 microspheres. The SEM and HRTEM observation...

DOAJ Open Access (DOAJ) DOI: 10.1590/1980-5373-mr-2018-0081

Dispersal homogenizes communities via immigration even at low rates in a simplified synthetic bacterial metacommunity

Stilianos Fodelianakis, Alexander Lorz, Adriana Valenzuela-Cuevas, Alan Barozzi et al. • Nature Communications (2019)

Fodelianakis et al. examine the role of immigration and selection as the means of community homogenisation in a bacterial metacommunity. They confirmed the role of immigration in homogenisation, even when immigration was four times slower t...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-019-09306-7

A Novel Anticancer Peptide Derived from <i>Bryopsis plumosa</i> Regulates Proliferation and Invasion in Non-Small Cell Lung Cancer Cells

Heabin Kim, Hyun-Taek Kim, Seung-Hyun Jung, Jong Won Han et al. • Marine Drugs (2023)

The discovery of new highly effective anticancer drugs with few side effects is a challenge for drug development research. Natural or synthetic anticancer peptides (ACPs) represent a new generation of anticancer agents with high selectivity...

DOAJ Open Access (DOAJ) DOI: 10.3390/md21120607

Composition, Demographic History, and Population Structures of Trichiurus

Kui-Ching Hsu, Mu-Rong Yi, Mu-Rong Yi, Sui Gu et al. • Frontiers in Marine Science (2022)

Sequences of the complete mitochondrial cytochrome oxidase subunit I gene were used to identify Trichiurus species and examine their population genetic structure and demographic history along the coast of China. Three Trichiurus species wer...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmars.2022.875042

Dynamic coastal pelagic habitat drives rapid changes in growth and condition of juvenile sockeye salmon (Oncorhynchus nerka) during early marine migration

Jessica Garzke, Ian Forster, Sean C. Godwin, Brett T. Johnson et al. • FACETS (2022)

Migrating marine taxa encounter diverse habitats that differ environmentally and in foraging conditions over a range of spatial scales. We examined body (RNA/DNA, length-weight residuals) and nutritional (fatty acid composition) condition o...

DOAJ Open Access (DOAJ) DOI: 10.1139/facets-2022-0068

Seabird Migration Strategies: Flight Budgets, Diel Activity Patterns, and Lunar Influence

Anne-Sophie Bonnet-Lebrun, Anne-Sophie Bonnet-Lebrun, Maria P. Dias, Maria P. Dias et al. • Frontiers in Marine Science (2021)

Every year, billions of birds undertake extensive migrations between breeding and non-breeding areas, facing challenges that require behavioural adjustments, particularly to flight timing and duration. Such adjustments in daily activity pat...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmars.2021.683071

Construction of Integrated Platform for Eco-Sustainable Tourism and Marketing in Southeast Asia Based on Machine Learning

Yi-Tui Chen, Yi-Min Li, Tzu-Wen Tseng • International Transactions on Electrical Energy Systems (2022)

Southeast Asia is one of the most popular tourist destinations in the world, and its tourism model is mainly based on ecological and sustainable tourism characteristics. It is a special practical exploration of this region. However, with th...

DOAJ Open Access (DOAJ) DOI: 10.1155/2022/6442618