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Poly (ADP-ribose) Polymerase Promoter Hypermethylation Predispose Females to Breast Cancer

Hussein Sabit, Shaimaa Nazir, Shimaa Abdel-Ghany, Osama A. Said et al. • Asian Pacific Journal of Cancer Biology (2019)

Being the most common cause of female deaths worldwide, breast cancer (BC) is intensively studied over the last two decades. In the present investigation, we evaluated the promoter methylation of three cancer-related genes; PARP-1, p21, and...

DOAJ Open Access (DOAJ) DOI: 10.31557/apjcb.2019.4.1.1-5

RETRACTED ARTICLE: Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus

Vassilis L. Souliotis, Konstantinos Vougas, Vassilis G. Gorgoulis, Petros P. Sfikakis • Arthritis Research & Therapy (2016)

Abstract Background Excessive autoantibody production characterizing systemic lupus erythematosus (SLE) occurs irrespective of the disease’s clinical status and is linked to increased lymphocyte apoptosis. Herein, we tested the hypothesis t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13075-016-1081-3

Flexibility-powered Pickering emulsion enhances mucus permeability to alleviate ulcerative colitis

Jiali Lv, Chen Cheng, Xinran Liu, Jinhua Song et al. • Journal of Nanobiotechnology (2025)

Abstract The physicochemical properties of oral drug delivery carriers significantly influence their interactions with the intestinal barrier, which, in turn, affect their in vivo fate and therapeutic efficacy. As a delivery system with a h...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03829-6

KRAS G12V neoantigen specific T cell receptor for adoptive T cell therapy against tumors

Dan Lu, Yuan Chen, Min Jiang, Jie Wang et al. • Nature Communications (2023)

Abstract KRAS mutations are broadly recognized as promising targets for tumor therapy. T cell receptors (TCRs) can specifically recognize KRAS mutant neoantigens presented by human lymphocyte antigen (HLA) and mediate T cell responses to el...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-023-42010-1

Impact of Prolonged COVID-19 Lockdown on Body Mass Index, Eating Habits, and Physical Activity of University Students in Bangladesh: A Web-Based Cross-Sectional Study

Md. Jamal Hossain, Foyez Ahmmed, Md. Robin Khan, Parisa Tamannur Rashid et al. • Frontiers in Nutrition (2022)

ObjectivesThis current study aims to assess the prevalence and factors associated with body mass index (BMI), dietary patterns, and the extent of physical activities among university students following the prolonged coronavirus disease 2019...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2022.873105

Developments in Exploring Fungal Secondary Metabolites as Antiviral Compounds and Advances in HIV-1 Inhibitor Screening Assays

Bruce Nzimande, John P. Makhwitine, Nompumelelo P. Mkhwanazi, Sizwe I. Ndlovu • Viruses (2023)

The emergence of drug-resistant Human Immunodeficiency Virus-1 strains against anti-HIV therapies in the clinical pipeline, and the persistence of HIV in cellular reservoirs remains a significant concern. Therefore, there is a continuous ne...

DOAJ Open Access (DOAJ) DOI: 10.3390/v15051039

Histone deacetylase 3 deletion in alveolar type 2 epithelial cells prevents bleomycin-induced pulmonary fibrosis

Rui Xiong, Boxin Geng, Wenyang Jiang, Yong Hu et al. • Clinical Epigenetics (2023)

Abstract Background Epithelial mesenchymal transformation (EMT) in alveolar type 2 epithelial cells (AT2) is closely associated with pulmonary fibrosis (PF). Histone deacetylase 3 (HDAC3) is an important enzyme that regulates protein stabil...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13148-023-01588-5

Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy

Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer (2024)

Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...

DOAJ Open Access (DOAJ) DOI: 10.1136/jitc-2023-008450

Comparative Phytochemical Analysis of the Aerial Parts of <i>Pelargonium radula</i> and <i>Geranium macrorrhizum</i> Cultivated in Bulgaria Using GC-MS and HPLC

Debora Sabotinova, Petya Boycheva, Nadezhda Ivanova, Velichka Andonova et al. • Pharmaceuticals (2026)

Background: Geraniaceae species are widely used in traditional medicine. Pelargonium radula and Geranium macrorrhizum are aromatic medicinal plants traditionally used in Bulgaria for their antimicrobial, anti-inflammatory, and wound-healing...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph19030346

Accomplishments in genome‐scale in silico modeling for industrial and medical biotechnology

Caroline B. Milne, Pan‐Jun Kim, James A. Eddy, Nathan D. Price • Biotechnology Journal (2009)

Driven by advancements in high-throughput biological technologies and the growing number of sequenced genomes, the construction of in silico models at the genome scale has provided powerful tools to investigate a vast array of biological sy...

OPENALEX Open Access DOI: https://doi.org/10.1002/biot.200900234 PMC: 3160784

Medical Biotechnology

Dylan R. Pillai • Clinical Infectious Diseases (2014)

Both the diagnosis and treatment of human disease have undergone radical changes since the seminal discoveries of molecular biology, magnetic resonance imaging, mass spectrometry, and vaccine development, to name but a few. Glick and collea...

OPENALEX DOI: https://doi.org/10.1093/cid/ciu510

Symbolic CSR and public responses among young Chinese social media users: dual mediation of skepticism and trust, moderated by algorithmic ethical perception

Tian Zhang, Tao Song, Muhammad Zaiamri Zainal Abidin, Mumtaz Aini Alivi • Frontiers in Communication (2026)

Drawing on signaling theory and the cognitive-affective framework, this study developed a moderated serial mediation model to explain how perceived symbolic CSR is associated with public responses in algorithm-mediated environments. It exam...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcomm.2026.1717505

CSNTSteg: Color Spacing Normalization Text Steganography Model to Improve Capacity and Invisibility of Hidden Data

Reema Thabit, Nur Izura Udzir, Sharifah Md Yasin, Aziah Asmawi et al. • IEEE Access (2022)

The rapid growth of online communication has increased the demand for secure communication. Most government entities, healthcare providers, the legal sector, financial and banking, and other industries are vulnerable to information security...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2022.3182712

Brauchen wir die Grippemittel Tamiflu und Relenza?

Schmidtke, Michaela, Mertens, Thomas, Gesellschaft für Virologie e.V. (GfV), Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten e.V. (DVV) et al. • GMS Infectious Diseases (2014)

Lately, several press releases as well as a parliamentary inquiry questioned the effectiveness of the neuraminidase inhibitors (NAI, oseltamivir and zanamivir) in concerns of therapy of influenza. However, in combination with the unfortunat...

DOAJ Open Access (DOAJ) DOI: 10.3205/id000014

Discrete Phase-Locked Loop Systems and Spreadsheets

Sergei Abramovich, Elena Kudryashova, Gennady A Leonov, Stephen J. Sugden • Spreadsheets in Education (2005)

This paper demonstrates the use of a spreadsheet in exploring non-linear difference equations that describe digital control systems used in radio engineering, communication and computer architecture. These systems, being the focus of intens...

DOAJ Open Access (DOAJ)

Globalization and Public Administration

Ali Farazmand • Public Administration Review (1999)

This article discusses globalization and its implications for public administration. Using a political economy approach, an analysis is made of different meanings and perspectives of globalization, of causes and consequences of globalizatio...

OPENALEX DOI: https://doi.org/10.2307/3110299

La transformación de la seguridad en Europa desde la caída del muro de Berlín. Una revisión crítica

Alberto Priego • Cuadernos Europeos de Deusto (2020)

En el año 1989 el símbolo de la división de Europa desaparecía gracias a un conjunto variado de circunstancias que convirtieron esa situación en insostenible. Uno de los ámbitos que más se vieron afectados fue el de la seguridad. Hoy 30 año...

DOAJ Open Access (DOAJ) DOI: 10.18543/ced-62-2020pp33-57

Fishermen Human Rights Protection and Sustainable Development in the Indonesian Marine Sector

Masitha Tismananda Kumala, Ria Tri Vinata, Titik Suharti, Peni Jati Setyowati • Lex Portus (2023)

Sustainable development is realized in various sectors, including marine and fisheries. Fishermen are the main pillars in advancing the marine and fisheries sector. The welfare of fishermen in Indonesia is not as good as Indonesia’s ambitio...

DOAJ Open Access (DOAJ) DOI: 10.26886/2524-101X.9.4.2023.2