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Showing 20 of 2,514 academic articles

Isolation, characterization, and genomic analysis of a novel phage WSPA with lytic activity against Serratia marcescens

Lijuan Li, Kunkun Li, Yu Mi, Xiumei Wu et al. • Microbiology Spectrum (2025)

ABSTRACT Serratia marcescens is an established pathogen implicated in hospital-acquired infections and is notorious for its propensity to form biofilms on medical devices, leading to persistent environmental contamination and increased infe...

DOAJ Open Access (DOAJ) DOI: 10.1128/spectrum.02716-24

Current Evidence on Gene-Based and Epigenetic Therapeutic, Diagnostic, and Prognostic Strategies in Epithelial-Derived Carcinomas: A Scoping Review

Joshua George Thomas, Mohammed Ayyub, Lovely M. Annamma, Prathibha Prasad et al. • Biomedicines (2026)

Background: Epithelial-derived carcinomas exhibit genomic instability due to genetic mutation and epigenetic dysregulation. Mechanisms such as DNA methylation, histone modifications, and noncoding RNA regulation may lead to tumor progressio...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines14102234

Photoluminescent Nanomaterials for Medical Biotechnology

Evgenii L. Guryev, Samah Shanwar, Andrei V. Zvyagin, Sergey Mikhailovich Deyev et al. • Acta Naturae (2021)

Creation of various photoluminescent nanomaterials has significantly expanded the arsenal of approaches used in modern biomedicine. Their unique photophysical properties can significantly improve the sensitivity and specificity of diagnosti...

OPENALEX cc-by DOI: https://doi.org/10.32607/actanaturae.11180 PMC: 8327149

Investigating the genetic makeup of the major histocompatibility complex (MHC) in the United Arab Emirates population through next-generation sequencing

Nour al dain Marzouka, Halima Alnaqbi, Amira Al-Aamri, Guan Tay et al. • Scientific Reports (2024)

Abstract The Human leukocyte antigen (HLA) molecules are central to immune response and have associations with the phenotypes of various diseases and induced drug toxicity. Further, the role of HLA molecules in presenting antigens significa...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-53986-1

International Journal of Medical Biotechnology & Genetics

Saket RD, Kol S, Tripathi AK, Singh SP et al. • International Journal of Medical Biotechnology & Genetics (2022)

International Journal of Medical Biotechnology & Genetics (IJMBG) ISSN: 2379-1020 is a comprehensive, peer reviewed journal devoted to Medical Biotechnology and Genetics. publishes original research, latest developments, review papers, scie...

OPENALEX cc-by DOI: https://doi.org/10.19070/2379-1020

Plant Virus–Derived Vectors: Applications in Agricultural and Medical Biotechnology

Peter E. Abrahamian, Rosemarie W. Hammond, John Hammond • Annual Review of Virology (2020)

Major advances in our understanding of plant viral genome expression strategies and the interaction of a virus with its host for replication and movement, induction of disease, and resistance responses have been made through the generation ...

OPENALEX DOI: https://doi.org/10.1146/annurev-virology-010720-054958

Flexibility-powered Pickering emulsion enhances mucus permeability to alleviate ulcerative colitis

Jiali Lv, Chen Cheng, Xinran Liu, Jinhua Song et al. • Journal of Nanobiotechnology (2025)

Abstract The physicochemical properties of oral drug delivery carriers significantly influence their interactions with the intestinal barrier, which, in turn, affect their in vivo fate and therapeutic efficacy. As a delivery system with a h...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03829-6

KRAS G12V neoantigen specific T cell receptor for adoptive T cell therapy against tumors

Dan Lu, Yuan Chen, Min Jiang, Jie Wang et al. • Nature Communications (2023)

Abstract KRAS mutations are broadly recognized as promising targets for tumor therapy. T cell receptors (TCRs) can specifically recognize KRAS mutant neoantigens presented by human lymphocyte antigen (HLA) and mediate T cell responses to el...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-023-42010-1

In Vitro Evaluation of Polihexanide, Octenidine and NaClO/HClO-Based Antiseptics against Biofilm Formed by Wound Pathogens

Grzegorz Krasowski, Adam Junka, Justyna Paleczny, Joanna Czajkowska et al. • Membranes (2021)

Chronic wounds complicated with biofilm formed by pathogens remain one of the most significant challenges of contemporary medicine. The application of topical antiseptic solutions against wound biofilm has been gaining increasing interest a...

DOAJ Open Access (DOAJ) DOI: 10.3390/membranes11010062

Comparative Phytochemical Analysis of the Aerial Parts of <i>Pelargonium radula</i> and <i>Geranium macrorrhizum</i> Cultivated in Bulgaria Using GC-MS and HPLC

Debora Sabotinova, Petya Boycheva, Nadezhda Ivanova, Velichka Andonova et al. • Pharmaceuticals (2026)

Background: Geraniaceae species are widely used in traditional medicine. Pelargonium radula and Geranium macrorrhizum are aromatic medicinal plants traditionally used in Bulgaria for their antimicrobial, anti-inflammatory, and wound-healing...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph19030346

Accomplishments in genome‐scale in silico modeling for industrial and medical biotechnology

Caroline B. Milne, Pan‐Jun Kim, James A. Eddy, Nathan D. Price • Biotechnology Journal (2009)

Driven by advancements in high-throughput biological technologies and the growing number of sequenced genomes, the construction of in silico models at the genome scale has provided powerful tools to investigate a vast array of biological sy...

OPENALEX Open Access DOI: https://doi.org/10.1002/biot.200900234 PMC: 3160784

Medical Biotechnology

Dylan R. Pillai • Clinical Infectious Diseases (2014)

Both the diagnosis and treatment of human disease have undergone radical changes since the seminal discoveries of molecular biology, magnetic resonance imaging, mass spectrometry, and vaccine development, to name but a few. Glick and collea...

OPENALEX DOI: https://doi.org/10.1093/cid/ciu510

Medical biotechnology

Firdos Alam Khan • CRC Press eBooks (2018)

This chapter explains the role of biotechnology in medicine and explores the process of making antibodies and hybridoma technology. It shows how vaccines are manufactured and discusses the significance of stem cell therapy and the related i...

OPENALEX DOI: https://doi.org/10.1201/9781315370767-9

Medical Biotechnology

Firdos Alam Khan • CRC Press eBooks (2020)

Biotechnology has many applications in medicine. While dealing with diseases, biotechnology tools and techniques have been used in the prevention, diagnosis, and cure of diseases. Through human genetics, biotechnology has found use in genet...

OPENALEX DOI: https://doi.org/10.1201/9781003024750-9

Medical Biotechnology - Approaches to become an Entrepreneur in Medical Biotechnology

Antony Vincent Samrot, Sanjay Preeth R., M. Bavanilatha • BENTHAM SCIENCE PUBLISHERS eBooks (2024)

Medical biotechnology is one of its branches which involves the application of medicine and biotechnology resources. Entrepreneurship is said to be the development of a new business making profits where innovation and creditability are cons...

OPENALEX DOI: https://doi.org/10.2174/9789815196115124010017