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Determinação do Perfil Ótimo de Alimentação de Substrato no Processo de Fermentação Alcoólica - Influência da Condição Inicial

Fran Sérgio Lobato • Trends in Computational and Applied Mathematics (2011)

A otimização dinâmica do processo de fermentação batelada alimentada, através do controle da vazão de alimentação de substrato, caracteriza um problema de controle singular de difícil solução devido à flutuação do índice diferencial e da...

DOAJ Open Access (DOAJ) DOI: 10.5540/tema.2011.012.01.0001

A compact model for the home healthcare routing and scheduling problem

Roberto Montemanni, Sara Ceschia, Andrea Schaerf • EURO Journal on Computational Optimization (2025)

Home healthcare has become more and more central in the last decades, due to the advantages it can bring to both healthcare institutions and patients. Planning activities in this context, however, presents significant challenges related to ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ejco.2024.100101

An adaptive cruise control system for autonomous vehicles using PRDC–CoROA-based hybrid optimization

M. Sivaramkrishnan, M. Siva Ramkumar, Kiruthika Balakrishnan, J. Isaac JoshuaRamesh Lalvani • Scientific Reports (2026)

Abstract An adaptive cruise control (ACC) system has a key role to play in enhancing the safety and stability of autonomous vehicles, along with ensuring improved ride quality through proper management of vehicle velocity and distance betwe...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-026-69261-4

Development and validation of a portable, point-of-care canine distemper virus qPCR test.

Ania Tomaszewicz Brown, Denise McAloose, Paul P Calle, Angelika Auer et al. • PLoS ONE (2020)

Canine distemper virus (CDV) is a multi-host pathogen that can cause significant mortality in domestic, wild terrestrial and marine mammals. It is a major conservation threat in some endangered species. Infection can result in severe respir...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0232044

Antimicrobial topical polymeric films loaded with Acetyl-11-keto-β-boswellic acid (AKBA), boswellic acid and silver nanoparticles: Optimization, characterization, and biological activity

Muhammad Jawad, Saurabh Bhatia, Ahmed Al-Harrasi, Sana Ullah et al. • Heliyon (2024)

The study examined the antimicrobial and antioxidant potential of pure Acetyl-11-keto-β-boswellic acid (AKBA), boswellic acid (70%) and AKBA loaded nanoparticles as topical polymeric films. The optimized concentration (0.05 % w/v) of pure A...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2024.e31671

Design and Optimization of Trastuzumab-Functionalized Nanolipid Carriers for Targeted Capecitabine Delivery: Anti-Cancer Effectiveness Evaluation in MCF-7 and SKBR3 Cells

Das S, Satapathy BS, Pattnaik G, Pattanaik S et al. • International Journal of Nanomedicine (2025)

Shubhashree Das,1 Bhabani Sankar Satapathy,2 Gurudutta Pattnaik,1 Sovan Pattanaik,3 Yahya Alhamhoom,4 Mohamed Rahamathulla,4 Mohammed Muqtader Ahmed,5 Ismail Pasha6 1Department of Pharmaceutics, School of Pharmacy and Life Sciences, Centuri...

DOAJ Open Access (DOAJ)

Evolutionary Algorithms in Health Technologies

Sai Ho Ling, Hak‐Keung Lam • Algorithms (2019)

Health technology research brings together complementary interdisciplinary research skills in the development of innovative health technology applications. Recent research indicates that artificial intelligence can help achieve outstanding ...

OPENALEX cc-by DOI: https://doi.org/10.3390/a12100202

A qualitative study exploring community pharmacists’ perspectives of child and adolescent mental healthcare

Irene A. Kretchy, Edem K. Blewuada, Akosua B. Debrah • Scientific African (2021)

Community pharmacists are involved in the health delivery sector through the provision of services that result in improved patient outcomes and optimization of pharmaceutical care. With growing concern about increasing prevalence of mental ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.sciaf.2021.e00969

Comparative assessment of patient education content generated by five large language models on post-stroke complications: A cross-sectional study of safety, accuracy, reliability, readability, and empathy

Long-Xian Liu, Huan-Huan Wang, Shuang Lu, Guo Yu et al. • Digital Health (2026)

Objective To compare the safety, accuracy, reliability, readability, and empathy of patient education content generated by five large language models (LLMs) for post-stroke complications. Methods This CHART-guided cross-sectional comparativ...

DOAJ Open Access (DOAJ) DOI: 10.1177/20552076261493266

G-Aligner: a graph-based feature alignment method for untargeted LC–MS-based metabolomics

Ruimin Wang, Miaoshan Lu, Shaowei An, Jinyin Wang et al. • BMC Bioinformatics (2023)

Abstract Background Liquid chromatography–mass spectrometry is widely used in untargeted metabolomics for composition profiling. In multi-run analysis scenarios, features of each run are aligned into consensus features by feature alignment ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12859-023-05525-4

Application of Gene Therapy to Oral Diseases

Seiichi Yamano, Kenji Inoue, Yoichiro Taguchi • Pharmaceutics (2025)

Gene therapy has emerged as a promising therapeutic approach across various oral diseases. This review examines current applications and future prospects of gene therapy in dentistry, focusing on five key areas: oral cancer, cancer-related ...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics17070859

Advances in microneedle-based drug delivery system for metabolic diseases: structural considerations, design strategies, and future perspectives

Yao Li, Qiu Chen, Tingting Wang, Zengkai Ji et al. • Journal of Nanobiotechnology (2025)

Abstract As the prevalence of metabolic diseases such as diabetes and obesity continue to rise, the search for more effective and convenient treatments has become a crucial issue in medical research. Microneedles (MNs), as an innovative dru...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03432-9