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Academic Articles & Research Papers
Showing 20 of 3,336 academic articles
Lucas Rodrigues Moraes, Pedro Leme Silva, Denise Battaglini, Patricia Rieken Macedo Rocco • Medicina
(2026)
Acute respiratory distress syndrome (ARDS) is a heterogeneous inflammatory lung injury marked by increased alveolar–capillary permeability, reduced respiratory system compliance, and impaired gas exchange. Despite advances in supportive car...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/medicina62020420
Martin Sindelar, Anna Kocurkova, Matej Simek, Pavel Roudnicky et al. • MicrobiologyOpen
(2026)
ABSTRACT The ability of gut microbes to degrade host‐ and diet‐derived glycans is central to microbiome ecology and host interactions, yet predicting these functions in silico remains challenging. Hyaluronan (HA), a glycosaminoglycan (GAG) ...
DOAJ
Open Access (DOAJ)
DOI: 10.1002/mbo3.70227
Adam H. Tencer, Jiuyang Liu, Jing Zhu, Nathaniel T. Burkholder et al. • Scientific Reports
(2022)
Abstract The E3 ubiquitin ligase HERC2 has been linked to neurological diseases and cancer, however it remains a poorly characterized human protein. Here, we show that the ZZ domain of HERC2 (HERC2ZZ) recognizes a mimetic of the Nt-R cargo ...
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Open Access (DOAJ)
DOI: 10.1038/s41598-022-10119-w
Maral Rahimzadeh, Majid Sadeghizadeh, Farhood Najafi, Seyed Shahriar Arab et al. • Materials Research Express
(2020)
During the last few decades, extensive studies have been conducted to elucidate the anti-cancer effects of curcumin. Despite promising results indicating curcumin could impede cancer cells ability thrive and proliferation, clinical applicat...
DOAJ
Open Access (DOAJ)
DOI: 10.1088/2053-1591/ab770f
Khushboo Singh, Roon Banerjee, Chandrakanta Potdar, Anisha Shaw et al. • Cells
(2026)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are among the most common genetic causes of Parkinson’s disease (PD), yet substantial heterogeneity exists among pathogenic variants. How mutations in distinct functional domains of LRRK2 di...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cells15040342
Victoria Vitkova, Vesela Yordanova, Galya Staneva, Ognyan Petkov et al. • Membranes
(2021)
Simple carbohydrates are associated with the enhanced risk of cardiovascular disease and adverse changes in lipoproteins in the organism. Conversely, sugars are known to exert a stabilizing effect on biological membranes, and this effect is...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/membranes11110847
Saul Vislei Simões da Silva, Orlando Maia Barboza, Jéssica Teles Souza, Érica Novaes Soares et al. • Molecules
(2021)
Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural mod...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules26226923
Li Rong, Haiyu Li, Zhaodong Li, Jing Ouyang et al. • Frontiers in Medicine
(2020)
Background and Objective: Chemotherapy and radiotherapy are effective treatment options for cervical cancer (CC), but their efficacy is limited by short survival rate of about 5 years particularly for advance stage CC. Bioinformatics analys...
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Open Access (DOAJ)
DOI: 10.3389/fmed.2020.608441
Balamurugan Jagadeesan, Leen Baert, Martin Wiedmann, Renato H. Orsi • Frontiers in Microbiology
(2019)
As WGS is increasingly used by food industry to characterize pathogen isolates, users are challenged by the variety of analysis approaches available, ranging from methods that require extensive bioinformatics expertise to commercial softwar...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmicb.2019.00947
O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok • Фармакоэкономика
(2025)
Background. Neurotransmitter adenosine and B-group vitamins have neuroprotective, remyelinizing and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular mechanisms of their synergistic effect ...
DOAJ
Open Access (DOAJ)
DOI: 10.17749/2070-4909/farmakoekonomika.2024.285
Shih-Ho Wang, Chin-Hu Wu, Chin-Chuan Tsai, Tai-Yu Chen et al. • Current Issues in Molecular Biology
(2022)
Taraxacum officinale (dandelion) is often used in traditional Chinese medicine for the treatment of cancer; however, the downstream regulatory genes and signaling pathways mediating its effects on breast cancer remain unclear. The present s...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cimb44050142
Wentong Chen, Mengxiao Ge, Shuangyi Sun, Hanxiao Zhang et al. • Scientific Reports
(2025)
Abstract As critical precursors to colorectal cancer (CRC), high-risk colorectal adenomas (HR-CRAs) lack effective chemopreventive strategies beyond endoscopic resection. We previously established a standardized protocol for culturing patie...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41598-025-32406-y
Lin J, Xue Y, Su W, Zhang Z et al. • International Journal of COPD
(2022)
Jie Lin,1,2,* Yanlong Xue,1,2,* Wenyan Su,1,2,* Zan Zhang,1,2 Qiu Wei,1,2 Tianxia Huang1,2 1Department of Respiratory and Critical Care, The Fifth Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530022, Peop...
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Open Access (DOAJ)
Weiwei Liu, Yan Wang, Zhimei Qiu, Ranzun Zhao et al. • PeerJ
(2020)
Background The occurrence of pathological cardiac fibrosis is attributed to tissue hypoxia. Circular RNAs play significant regulatory roles in multiple cardiovascular diseases and are involved in the regulation of physiological and pathophy...
DOAJ
Open Access (DOAJ)
DOI: 10.7717/peerj.9796
Rita Patrizia Aquino, Teresa Mencherini, Pierluigi Mazzei, Tiziana Esposito et al. • Carbohydrate Polymer Technologies and Applications
(2025)
This study reports on the development of a carbohydrate-based spray-dried microparticulate system (F-CHES) conceived for the stabilization and foliar delivery of polyphenol-rich plant extracts for sustainable phyto defense applications. Che...
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Open Access (DOAJ)
DOI: 10.1016/j.carpta.2025.101023
Qiang Wang, Qiang Wang, Yujun Ji, Torkel B. Brismar et al. • Frontiers in Surgery
(2021)
Background: To evaluate the feasibility and efficacy of sequential portal vein embolization (PVE) and radiofrequency ablation (RFA) (PVE+RFA) as a minimally invasive variant for associating liver partition and portal vein ligation for stage...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fsurg.2021.741352
Chao Ren, Peiyuan Yin, Neng Ren, Zhe Wang et al. • Stem Cell Research & Therapy
(2018)
Abstract Recent studies have suggested that the regulation of endogenous neural stem cells (NSCs) or transplanting of exogenous nerve cells are the newest and most promising methods for the treatment of dementia and other neurological disea...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s13287-018-0807-3
Müjgan Ercan, Emiş Deniz Akbulut, Ayşen Caniklioğlu, Esra Fırat Oğuz et al. • Journal of Mass Spectrometry and Advances in the Clinical Lab
(2025)
Introduction: Free amino acid (FAA) analysis plays a crucial role in diagnosing and monitoring inborn errors of metabolism, assessing nutritional status, and identifying metabolic imbalances associated with various diseases. This study aime...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.jmsacl.2025.04.010
K. B. Sumena, N. S. Sunilkumar, K. M. Lucy, S. Maya et al. • Journal of Veterinary and Animal Sciences
(2019)
Present study was conducted with the aim to understand the morphological features
of skull of barred jungle owlet.The head of the owletwascollected from the specimen brought for post-mortem, processed and morphological studies were conduct...
DOAJ
Open Access (DOAJ)
Alireza Azarberahman, Mahmoodreza Mohammadnejadi Modi • Journal of Business and Socio-Economic Development
(2025)
PurposeThis research examines the structure of financial markets by integrating game theory and fuzzy logic. The objective is to develop a differential game model that analyzes competition among financial firms within a specific industry.De...
DOAJ
Open Access (DOAJ)
DOI: 10.1108/JBSED-03-2024-0030