Academic Articles & Research Papers

ChsA, a Class Ⅱ Chitin Synthase, Contributes to Asexual Conidiation, Mycelial Morphology, Cell Wall Integrity, and the Production of Enzymes and Organic Acids in <i>Aspergillus niger</i>

Chitin synthases (CHSs) are vital enzymes for the synthesis of chitin and play important and differential roles in fungal development, cell wall integrity, environmental adaptation, virulence, and metabolism in fungi. However, except for Ch...

The Challenge of Timely, Responsive and Rigorous Ethics Review of Disaster Research: Views of Research Ethics Committee Members.

Research conducted following natural disasters such as earthquakes, floods or hurricanes is crucial for improving relief interventions. Such research, however, poses ethical, methodological and logistical challenges for researchers. Oversig...

The effects of adapted physical education sessions on the empathy of female students with overweight

The global prevalence of childhood and adolescent overweight and obesity increases rapidly. Physical activity plays a major role in the prevention of obesity. The present study aimed to analyze the effect of adapted basketball sessions acco...

A Novel MRAC Scheme for Output Tracking

This paper puts forward a novel output feedback model reference adaptive control (MRAC) scheme for solving an adaptive output tracking problem. The proposed control scheme only needs a scalar function to be updated online, which decreases t...

OP47 New Health Technology Assessment Framework For Digital Health Technologies

Introduction Experts emphasize the necessity of reconsidering the approaches used in the health technology assessment (HTA) of digital health technologies (DHTs) to adequately address their particular characteristics. In this context, the A...

Digital prevention of depression for farmers? A qualitative study on participants' experiences regarding determinants of acceptance and satisfaction with a tailored guided internet intervention program

Introduction: Farmers, forest workers and gardeners have a higher risk of developing depression compared to other occupational populations. As part of the German pilot project “With us in balance”, the potential of six guided internet- and ...

The efficacy of Narrative Exposure Therapy for Children (KIDNET) as a treatment for traumatized young refugees versus treatment as usual: update to the study protocol for the multi-center randomized controlled trial YOURTREAT

Abstract Background The trial YOURTREAT aims to compare the pragmatic, short-term psychotherapy Narrative Exposure Therapy for Children (KIDNET) with treatment as usual (TAU) for the treatment of young refugees in Germany. This update outli...

A Personalized Gait Parameter Prediction-Based Speed-Adaptive Control Method for Hybrid Active-Passive Intelligent Prosthetic Knee

To address the limitations of current prosthetic knees that lack personalized adaptability to users’ gait characteristics and walking speeds, this study proposes a personalized gait parameter prediction–based speed-adaptive control method f...

DeltaProt: a software toolbox for comparative genomics

Abstract Background Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding of environmental adaptations of proteins, orthologous ...

Cross-cultural adaptation and psychometric properties of the Kessler Scale of Psychological Distress to a traumatic brain injury population in Swahili and the Tanzanian Setting

Abstract Background To evaluate the psychometric properties of a Swahili version of the Kessler Psychological Distress scale in an injury population in Tanzania. Methods Swahili version of the Kessler Psychological Distress scale was develo...

Adaptation of the Stakeholders’ Walkability/Wheelability Audit in Neighborhoods (SWAN) Tool for Individuals With Diverse Disabilities: Protocol for a Mixed Methods Study

BackgroundThe prevalence of sensory, cognitive, and mobility disabilities in Canada underscores the need to address environmental barriers. This study adapts and validates the Stakeholders’ Walkability/Wheelability Audit in Neighborhoods (S...

Science and Practice: A Case for Medical Informatics as a Local Science of Design

Because scientific research is guided by concerns for uncovering "fundamental truths," its time frame differs from that of design, development, and practice, which are driven by immediate needs for practical solutions. In medicine, however,...

Psychometric analysis of the questionnaires for the assessment of upper limbs available in their Italian version: a systematic review of the structural and psychometric characteristics

Abstract Introduction There is no systematic review that analyzes the psychometric properties of questionnaires in Italian. Previous studies have analyzed the psychometric characteristics of instruments for the measurement of pathologies of...

Friends with Social Benefits: Host-Microbe Interactions as a Driver of Brain Evolution and Development?

The tight association of the human body with trillions of colonizing microbes that we observe today is the result of a long evolutionary history. Only very recently have we started to understand how this symbiosis also affects brain functio...

Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content>

ABSTRACT Infections caused by highly successful clones of hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) are a major public health burden. The globally dominant sequence type 239 (ST239) HA-MRSA clone has persiste...

Flexibility-powered Pickering emulsion enhances mucus permeability to alleviate ulcerative colitis

Abstract The physicochemical properties of oral drug delivery carriers significantly influence their interactions with the intestinal barrier, which, in turn, affect their in vivo fate and therapeutic efficacy. As a delivery system with a h...

Adaptive Cloud-Based Extended Reality: Modeling and Optimization

Extended Reality (XR) &#x2014; which includes Virtual Reality and Augmented Reality &#x2014; promises to bring the virtual and telepresence experience to another level. Unfortunately, solutions leveraging these technologies require special ...

Developing and defining core climate and environmental epidemiology competencies for field epidemiology training programs in the Eastern Mediterranean Region: a Delphi study

BackgroundClimate change, environmental degradation, and chemical hazards increasingly shape population health risks, particularly in the Eastern Mediterranean Region (EMR), where water scarcity, rapid urbanization, conflict, and fragile he...

Editorial: Institutional adaptation and transformation for climate resilience

Transnational ties with the ethnic homeland: the case of Korean women of the CIS in marital migration

Every year, tens of thousands of women from developing countries cross borders to marry men from developed countries. Men in Western Europe and the United States are looking for future partners from Russia and Eastern Europe, while men in E...