Academic Articles & Research Papers

Correction: Modeling relationships between iron status, behavior, and brain electrophysiology: evidence from a randomized study involving a biofortified grain in Indian adolescents

Camel Milk Targeting Insulin Receptor—Toward Understanding the Antidiabetic Effects of Camel Milk

Camel milk (CM) is known for its beneficial virtues in the human diet and health. This includes its antidiabetic properties demonstrated in many in vitro and in vivo studies. Nevertheless, the scientific rationale behind the molecular and c...

Anti-inflammatory activity of two varieties of pumpkin seed oil in an adjuvant arthritis model in rats

The aim of the present research was to evaluate the anti-inflammatory activity of pumpkin seed oils (PSOs) of an Egyptian and European variety, in a rat model of adjuvant arthritis. Edema thickness, plasma tumor necrosis factor-α (TNF-α) an...

Protocol to measure human IL-6 secretion from CAR T cell-primed macrophage and monocyte lineage cells in vitro and in vivo using humanized mice

Summary: Chimeric antigen receptor (CAR) T cell therapy often causes serious toxicities, such as cytokine release syndrome (CRS), mainly due to interleukin-6 (IL-6) secreted by monocyte lineage cells. Here, we describe a protocol to generat...

PENGEMBANGAN MODEL KOLABORASI JIGSAW ROLE PLAYING SEBAGAI UPAYA PENINGKATAN KEMAMPUAN BEKERJASAMA SISWA KELAS V SD PADA PELAJARAN IPS

Penelitian bertujuan untuk mengembangkan model kolaborasi jigsaw, role playing untuk meningkatkan kemampuan bekerjasama siswa yang valid, efektif dan praktis. Metode penelitian adalah penelitian dan pengembangan (R&D). Tahap uji coba pe...

Robotic Arthroplasty Clinical and cost Effectiveness Randomised controlled trial (RACER-knee): a study protocol

Introduction Robotic-assisted knee replacement systems have been introduced to healthcare services worldwide in an effort to improve clinical outcomes for people, although high-quality evidence that they are clinically, or cost-effective re...

Evaluation of clinical quality improvement interventions: feasibility of an integrated approach

Abstract Background Cardiovascular diseases (CVD) are the largest cause of death and disability in Australia. Australian national guidelines for the primary prevention of CVD recommend that all adults without CVD and aged 45 years or more a...

VirtualToxLab™ - In silico prediction of the toxic (endocrine-disrupting) potential of drugs, chemicals and natural products. Two years and 2,000 compounds of experience: a progress report

The VirtualToxLab™ is an in silico tool for predicting the toxic (endocrine-disrupting) potential of drugs, chemicals and natural products. It is based on a fully automated protocol and calculates the binding affinity of any molecule of int...

Modeling Lay People’s Ethical Attitudes to Organ Donation: A Q-Methodology Study

Muhammad M Hammami, 1, 2 Muhammad B Hammami, 3 Reem Aboushaar 4 1Clinical Studies and Empirical Ethics Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia; 2Alfaisal University College of Medicine, Riyadh...

The principle of the 3Rs between aspiration and reality

The Principle of the 3Rs is widely recognised as the methodological and ethical backbone of contemporary animal research. Different authors also stress the reciprocal links among the 3Rs, and how these often complement and reinforce each ot...

Comparative study of strongly and weakly coupled data assimilation with a global land–atmosphere coupled model

This study explores coupled land–atmosphere data assimilation (DA) for improving weather and hydrological forecasts by assimilating soil moisture (SM) data. This study integrates a land DA component into a global atmospheric DA system of th...

Methane and carbon dioxide fluxes over a lake: comparison between eddy covariance, floating chambers and boundary layer method

Freshwaters bring a notable contribution to the global carbon budget by emitting both carbon dioxide (CO2) and methane (CH4) to the atmosphere. Global estimates of freshwater emissions traditionally use a wind-speed-based gas transfer ve...

Agricultural Use of Lands Affected by Deep-Seated Landslides in the Transylvanian Basin and Its Consequences on Soil Physicochemical Properties

Land leveling deep-seated landslides for agricultural use alters soil profile integrity and soil functionality. In the mid-20th century, such interventions in the Transylvanian Basin (Romania) involved grading and converting landslide bodie...

Reproductive Biology of Female Pacific Halibut (Hippoglossus stenolepis) in the Gulf of Alaska

Developing a robust understanding of Pacific halibut reproductive biology is essential to understanding the different components (e.g. maturity) that determine the reproductive output of the species and, therefore, for estimating the relati...

NLRP3 Inflammasome-Mediated Pyroptosis Pathway Contributes to the Pathogenesis of Candida albicans Keratitis

PurposeFungal keratitis is a sight-threatening corneal infection caused by fungal pathogens, and the pathogenic mechanisms have not been fully elucidated. The aim of this study was to determine whether NOD-like receptor family pyrin domain ...

Topograpaphic controls and future vulnerability of recurrent snowpatches in the Gaspé Peninsula (Québec, Canada)

Snowpatches are sensitive indicators of environmental change in mountain environments because their occurrence reflects interactions among topography, snow redistribution, and climate. Despite their ecological and geomorphological significa...

Assessing the impact of forest structure disturbances on the arboreal movement and energetics of orangutans—An agent-based modeling approach

Agent-based models have been developed and widely employed to assess the impact of disturbances or conservation management on animal habitat use, population development, and viability. However, the direct impacts of canopy disturbance on th...

Perceived community environment and depressive symptoms among older adults in China: a cross-sectional analysis of physical activity as a moderator

IntroductionPerceived community environment is an important contextual factor related to depressive symptoms in later life. However, few studies have examined whether physical activity (PA), a modifiable behavioral factor, moderates this as...

Impact of Electronic Customer Relationship Management on Purchase Intention with mediation role of Customer E-Satisfaction: evidence from Egyptian SMEs

The purpose of this research is to empirically investigate the impact of electronic customer relationship management (E-CRM) on purchase Intention with mediation role of Customer E-Satisfaction: evidence from Egyptian SMEs. The methodology ...

Sustainability-oriented leadership and organizational citizenship behavior for the environment: How green job demands and AI literacy shape the relationship

This study examines the relationship between sustainable leadership and organizational citizenship behavior for the environment among hotel employees in Vietnam. The proposed research model investigates the mediating roles of green absorpti...