Reset
Showing 20 of 401 academic articles

Detection Techniques for Synthetic Cannabinoids in Body Fluids and Tissues: A Systematic Review

Sachil Kumar, Tulsidas R. Baggi • Journal of Forensic Science and Medicine (2026)

Synthetic cannabinoids (SCs), originally developed for research purposes in the 1960s, have emerged as a significant concern in clinical and forensic toxicology due to their widespread abuse and unpredictable toxicological effects. These co...

DOAJ Open Access (DOAJ) DOI: 10.4103/jfsm.jfsm_128_25

The Effect of Yinchenhao Decoction on the Pharmacokinetic Profile of Futibatinib by HPLC-MS/MS

Chunfu Wang, Songmao Liang, Jiachen Xu, Yingfan Zhai et al. • Separations (2024)

Futibatinib is an excellent fibroblast growth factor receptor 1–4 (FGFR 1–4) inhibitor that exhibits selective anti-tumor activeness against FGFR-deregulated tumors. A new high-performance liquid chromatography-tandem mass spectrometry (HPL...

DOAJ Open Access (DOAJ) DOI: 10.3390/separations11070213

TRACK-CF prospective cohort study: Understanding early cystic fibrosis lung disease

Eva Steinke, Eva Steinke, Eva Steinke, Olaf Sommerburg et al. • Frontiers in Medicine (2023)

BackgroundLung disease as major cause for morbidity in patients with cystic fibrosis (CF) starts early in life. Its large phenotypic heterogeneity is partially explained by the genotype but other contributing factors are not well delineated...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2022.1034290

System 2 Thinking in OpenAI’s o1-Preview Model: Near-Perfect Performance on a Mathematics Exam

Joost C. F. de Winter, Dimitra Dodou, Yke Bauke Eisma • Computers (2024)

The processes underlying human cognition are often divided into System 1, which involves fast, intuitive thinking, and System 2, which involves slow, deliberate reasoning. Previously, large language models were criticized for lacking the de...

DOAJ Open Access (DOAJ) DOI: 10.3390/computers13110278

HEALTH TECHNOLOGY ASSESSMENT IN GREECE

Lycurgus L. Liaropoulos, Δάφνη Καϊτελίδου • International Journal of Technology Assessment in Health Care (2000)

In 1983 a health reform aimed to assure universal coverage and equity in the distribution of services in Greece. The reform implied state responsibility for the financing and delivery of services and a reduction of the private sector. The m...

OPENALEX DOI: https://doi.org/10.1017/s0266462300101084

Development and validation of a portable, point-of-care canine distemper virus qPCR test.

Ania Tomaszewicz Brown, Denise McAloose, Paul P Calle, Angelika Auer et al. • PLoS ONE (2020)

Canine distemper virus (CDV) is a multi-host pathogen that can cause significant mortality in domestic, wild terrestrial and marine mammals. It is a major conservation threat in some endangered species. Infection can result in severe respir...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0232044

Neurotoxicity of PM<sub>2.5</sub>-Bound Multi-Pollutant Mixtures in Parkinson’s Disease: Exploring the <i>INPP5D</i>/SHIP1-PI3K-AKT Axis via an Integrative Multi-Omics Study

Lufei Chen, Chaoxian Dai, Zhenfang Wu, Yuhan Lin et al. • Journal of Xenobiotics (2026)

Accumulating epidemiological evidence links ambient PM2.5 exposure to elevated Parkinson’s disease (PD) risk, yet the neurotoxicity triggered by PM2.5 multi-pollutant mixtures under real co-exposure scenarios remains insufficiently elucidat...

DOAJ Open Access (DOAJ) DOI: 10.3390/jox16060184

Developing a nomogram to predict recurrent intussusception after pneumatic reduction of primary intussusception in children

Jie Liu, Danping Zeng, Zhihui Jiang, Wenli Xiu et al. • BMC Surgery (2024)

Abstract Backgroud Intussusception is a common acute abdominal disease in children, often leading to acute ileus in infants and young children. Objective This study aimed to develop and validate a nomogram for predicting recurrent intussusc...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12893-024-02578-x

Further validation of the Chinese short Warwick Edinburgh mental wellbeing scale in the adult population of Macau: an application of classic test theory and item response theory

Lawrence T. Lam, Lawrence T. Lam, Lawrence T. Lam, Mary K. Lam • Frontiers in Psychiatry (2025)

BackgroundThis study aims to validate the Chinese version of the Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS) by employing both Classical Test Theory (CTT) and Item Response Theory (IRT) approaches.MethodsData were gathered thr...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyt.2025.1528509

Computable phenotype for real-world, data-driven retrospective identification of relapse in ANCA-associated vasculitis

Vladimir Tesar, Conor Judge, John Kelleher, Zdenka Hrušková et al. • RMD Open (2024)

Objective ANCA-associated vasculitis (AAV) is a relapsing-remitting disease, resulting in incremental tissue injury. The gold-standard relapse definition (Birmingham Vasculitis Activity Score, BVAS&gt;0) is often missing or inaccurate in re...

DOAJ Open Access (DOAJ) DOI: 10.1136/rmdopen-2023-003962

Design and Optimization of Trastuzumab-Functionalized Nanolipid Carriers for Targeted Capecitabine Delivery: Anti-Cancer Effectiveness Evaluation in MCF-7 and SKBR3 Cells

Das S, Satapathy BS, Pattnaik G, Pattanaik S et al. • International Journal of Nanomedicine (2025)

Shubhashree Das,1 Bhabani Sankar Satapathy,2 Gurudutta Pattnaik,1 Sovan Pattanaik,3 Yahya Alhamhoom,4 Mohamed Rahamathulla,4 Mohammed Muqtader Ahmed,5 Ismail Pasha6 1Department of Pharmaceutics, School of Pharmacy and Life Sciences, Centuri...

DOAJ Open Access (DOAJ)

Cross-national validation of the MHQoL: psychometric evaluation and open-source tools for assessing mental health quality of life

Beatriz Olaya, Christina Maria van der Feltz-Cornelis, Leona Hakkaart-van Roijen, Frederick W Thielen et al. • BMJ Open (2026)

Objectives To validate the cross-national psychometric properties of the Mental Health Quality of Life questionnaire (MHQoL) and to develop an open-source toolbox for its scoring, transformation and presentation.Design Secondary analysis of...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2025-108598

Advances in High Throughput Proteomics Profiling in Establishing Potential Biomarkers for Gastrointestinal Cancer

Md Zahirul Islam Khan, Shing Yau Tam, Helen Ka Wai Law • Cells (2022)

Gastrointestinal cancers (GICs) remain the most diagnosed cancers and accounted for the highest cancer-related death globally. The prognosis and treatment outcomes of many GICs are poor because most of the cases are diagnosed in advanced me...

DOAJ Open Access (DOAJ) DOI: 10.3390/cells11060973

Development of an evaluation framework for health information communication technology in contemporary pharmacy practice

Ayomide Ogundipe, Tin Fei Sim, Lynne Emmerton • Exploratory Research in Clinical and Social Pharmacy (2023)

Background: Health information communication technology (ICT) has rapidly evolved in contemporary pharmacy practice worldwide. The Australian healthcare system is experiencing a paradigm shift to real-time interconnectivity for practitioner...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rcsop.2023.100252

Genome-wide association analysis uncovers rice blast resistance alleles of Ptr and Pia

Julian R. Greenwood, Vanica Lacorte-Apostol, Thomas Kroj, Jonas Padilla et al. • Communications Biology (2024)

Abstract A critical step to maximize the usefulness of genome-wide association studies (GWAS) in plant breeding is the identification and validation of candidate genes underlying genetic associations. This is of particular importance in dis...

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-024-06244-z

Development of an in vitro system to study oral biofilms in real time through impedance technology: validation and potential applications

Alex Mira, Elena Buetas, Bob T. Rosier, Danuta Mazurel et al. • Journal of Oral Microbiology (2019)

Background and objectives: We have developed a standardized, easy-to-use in vitro model to study single- and multiple-species oral biofilms in real time through impedance technology, which elucidates the kinetics of biofilm formation in 96-...

DOAJ Open Access (DOAJ) DOI: 10.1080/20002297.2019.1609838

Molecular Informatics, Chemometrics, and Sensory Omics for Constructing an Umami Peptide Cluster Library Across the Entire Lager Beer Brewing Process

Yashuai Wu, Ruiyang Yin, Wenjing Tian, Wanqiu Zhao et al. • Foods (2026)

Umami taste in lager beer not only determined body fullness and the backbone of aftertaste, but also affected the controllability and interpretability of flavor expression across the entire brewing process. Based on stage-wise sampling, pep...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods15040641

The Colorectal Cancer Screening Programme in the Basque Country: obtaining a good performance by means of professional collaboration

Isabel Portillo, Isabel Idigoras, Isabel Bilbao, Jose Luis Hurtado et al. • International Journal of Integrated Care (2019)

Introduction: The Basque Health Service approved the Colorectal Cancer (CRC) screening programme in 2008; targeted at residents (50 to 69 years old) estimated 598,201 by biennial faecal immunochemical test (FIT) and colonoscopy in positive ...

DOAJ Open Access (DOAJ) DOI: 10.5334/ijic.s3166

Assessing Acceptance and Intention to Use of Home Telemonitoring Among Patients with Liver Cirrhosis: Development and Initial Psychometric Validation of a TAM-Based Questionnaire

Ruxandra-Cristina Marin, Horia Păunescu, Călin Muntean, Daniel Vasile Balaban et al. • Diagnostics (2026)

Background/Objectives: Liver cirrhosis (LC) is a major cause of morbidity and mortality requiring continuous monitoring and early recognition of clinical deterioration. Home telemonitoring is increasingly considered a supportive strategy fo...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics16162635