Reset
Showing 20 of 494 academic articles

Depressive phenotype shapes behavioral, neuroendocrine and molecular responses to repetitive transcranial magnetic stimulation in preclinical models of depression

Marta Boffa, Marta Boffa, Sara Spalletti, Sara Spalletti et al. • Frontiers in Molecular Neuroscience (2026)

IntroductionRepetitive transcranial magnetic stimulation (rTMS) is an established non-invasive treatment for treatment-resistant depression (TRD), yet its neurobiological mechanisms remain only partially understood. We investigated whether ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2026.1939025

Recent advances in benzo[a]phenoxazine-based fluorescent probes: a review and perspectives

Kalayou Hiluf Gebremdhin, Mebrahtom Gebrelibanos Hiben, Hagos Feleke Gebremariam, Hagos Hailu Kassegn et al. • Journal of Photochemistry and Photobiology (2026)

Benzo[a]phenoxazine (BPO) based molecules have been recently emerged as a new class of near-infrared (NIR) fluorophore for image-guided diagnosis in cancer research. The successful application of BPOs as NIR fluorophore in biomedical resear...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jpap.2026.100280

Hormonal Influences on ADC Values in Breast Tissues: A Scoping Review of DWI in Pre- and Post-menopausal Women [version 3; peer review: 2 approved]

Neil Barnes Abraham, Abhimanyu Pradhan, Suresh Sukumar, Sneha Ravichandran et al. • F1000Research (2025)

Background Breast cancer remains a significant global health concern, with early diagnosis and risk factor identification crucial for improving outcomes. Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) measurements...

DOAJ Open Access (DOAJ) DOI: 10.12688/f1000research.153999.3

Health technology and health technology assessment

Konrad Obermann, Christian Thielscher • Medical economics (2021)

In addition to the doctor, technology is an essential aspect of healthcare. In many parts of the world, a visit to the doctor does not feel complete without a prescription for a drug. Advanced laboratory and imaging technology is indispensa...

OPENALEX DOI: https://doi.org/10.1017/9781788211918.015

Oh brother, where art tau? Amyloid, neurodegeneration, and cognitive decline without elevated tau

Lauren E. McCollum, Sandhitsu R. Das, Long Xie, Robin de Flores et al. • NeuroImage: Clinical (2021)

Mild cognitive impairment (MCI) can be an early manifestation of Alzheimer’s disease (AD) pathology, other pathologic entities [e.g., cerebrovascular disease, Lewy body disease, LATE (limbic-predominant age-related TDP-43 encephalopathy)], ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102717

Disrupted Functional Connectivity of Cornu Ammonis Subregions in Amnestic Mild Cognitive Impairment: A Longitudinal Resting-State fMRI Study

Hui Li, Hui Li, Xiuqin Jia, Xiuqin Jia et al. • Frontiers in Human Neuroscience (2018)

Background: The cornu ammonis (CA), as part of the hippocampal formation, represents a primary target region of neural degeneration in amnestic mild cognitive impairment (aMCI). Previous studies have revealed subtle structural deficits of t...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnhum.2018.00413

ACHENY: A standard Chenopodiaceae image dataset for deep learning models

Ahmad Heidary-Sharifabad, Mohsen Sardari Zarchi, Sima Emadi, Gholamreza Zarei • Data in Brief (2021)

This paper contains datasets related to the “Efficient Deep Learning Models for Categorizing Chenopodiaceae in the wild” (Heidary-Sharifabad et al., 2021). There are about 1500 species of Chenopodiaceae that are spread worldwide and often a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2021.107478

Deep learning-based multimodal data fusion in bone tumor management: Advances in clinical decision support

Tongtong Huo, Wei Wu, Xiaoliang Chen, Mingdi Xue et al. • Intelligent Oncology (2025)

Bone tumors (BTs)—including osteosarcoma, Ewing sarcoma, and chondrosarcoma—are rare but biologically complex malignancies characterized by pronounced heterogeneity in anatomical location, histological subtype, and molecular alterations. Re...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.intonc.2025.06.005

The thalamus and its subregions – a gateway to obsessive-compulsive disorder

C. Weeland, C. Vriend, Y. Van Der Werf, C. Huyser et al. • European Psychiatry (2022)

Introduction Higher thalamic volume has been found in children with obsessive-compulsive disorder (OCD) and children with clinical-level symptoms within the general population (Boedhoe et al. 2017, Weeland et al. 2021a). Functionally distin...

DOAJ Open Access (DOAJ) DOI: 10.1192/j.eurpsy.2022.239

Fast Healthcare Interoperability Resources (FHIR) for Interoperability in Health Research: Systematic Review

Carina Nina Vorisek, Moritz Lehne, Sophie Anne Ines Klopfenstein, Paula Josephine Mayer et al. • JMIR Medical Informatics (2022)

BackgroundThe standard Fast Healthcare Interoperability Resources (FHIR) is widely used in health information technology. However, its use as a standard for health research is still less prevalent. To use existing data sources more efficien...

DOAJ Open Access (DOAJ) DOI: 10.2196/35724

Pitfalls in the use of whole slide imaging for the diagnosis of central nervous system tumors: A pilot study in surgical neuropathology

Melike Pekmezci, Sanem Pinar Uysal, Yelda Orhan, Tarik Tihan et al. • Journal of Pathology Informatics (2016)

Background: Whole slide imaging (WSI) finds increasingly higher value in everyday surgical pathology in addition to its well-established use for educational and research purposes. However, its diagnostic utility, especially in subspecialty ...

DOAJ Open Access (DOAJ) DOI: 10.4103/2153-3539.181769

Dopamine transporter binding in symptomatic controls and healthy volunteers: Considerations for neuroimaging trials

Emma A. Honkanen, Mikael Eklund, Simo Nuuttila, Tommi Noponen et al. • NeuroImage: Clinical (2021)

Objective: To evaluate possible differences between brain dopamine transporter (DAT) binding in a group of symptomatic parkinsonism patients without dopaminergic degeneration and healthy individuals. Background: Dopaminergic neuroimaging st...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102807

Longitudinal analysis of white matter and cortical lesions in multiple sclerosis

Mário João Fartaria, Tobias Kober, Cristina Granziera, Meritxell Bach Cuadra • NeuroImage: Clinical (2019)

Purpose: The goals of this study were to assess the performance of a novel lesion segmentation tool for longitudinal analyses, as well as to validate the generated lesion progression map between two time points using conventional and non-co...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2019.101938

Image-Based RCS Estimation from Near-Field Data

Tushar Rajvanshi, Maria Antonia Maisto, Angela Dell’Aversano, Raffaele Solimene • Journal of Imaging (2019)

This paper deals with the problem of estimating the RCS from near-field data by image-based approaches. In particular, a rigorous focusing procedure based on a weighted adjoint scheme, which is also applicable to an arbitrary measurement cu...

DOAJ Open Access (DOAJ) DOI: 10.3390/jimaging5060061

Identification of brain regions predicting epileptogenesis by serial [18F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy

Vera Russmann, Matthias Brendel, Erik Mille, Angela Helm-Vicidomini et al. • NeuroImage: Clinical (2017)

Excessive activation of inflammatory signaling pathways seems to be a hallmark of epileptogenesis. Positron emission tomography (PET) allows in vivo detection of brain inflammation with spatial information and opportunities for longitudinal...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2017.04.003

Multidetector Computed Tomography (MDCT) Findings of Complications of Acute Cholecystitis. A Pictorial Essay

Fabio Sandomenico, Luca Sanduzzi, Emilia La Verde, Emilio Vicenzo et al. • Tomography (2022)

Acute cholecystitis stands out as one of the most common surgical pathologies that should always be considered in a right-upper abdominal pain emergency. For this, the importance of a correct diagnosis is well described. However, it has bee...

DOAJ Open Access (DOAJ) DOI: 10.3390/tomography8020095

Penetration and familiarity of false belief on neuroscience among students and its modifiability

Takeshi Hatta, Taketoshi Hatta, Kazuhisa Todayama, Minoru Karasawa • Journal of Human Environmental Studies (2010)

In Study 1, the degrees of penetration and familiarity of false belief on neuroscience, especially brain imaging, among students were surveyed using a questionnaire technique. A total number of 485 students from medical school, school of nu...

DOAJ Open Access (DOAJ) DOI: 10.4189/shes.8.155

Early Retinal Microvascular Alterations in Young Type 1 Diabetic Patients without Clinical Retinopathy

Alexandra Oltea Dan, Alin Ștefănescu-Dima, Andrei Teodor Bălășoiu, Ileana Puiu et al. • Diagnostics (2023)

The purpose of this study is to identify and quantify preclinical changes with the help of optical coherence tomography angiography (OCTA) within the retinal microcirculation of young type 1 diabetes (T1D) patients without clinical signs of...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics13091648

From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder

Chunyu Pan, Ying Ma, Lifei Wang, Yan Zhang et al. • Brain Sciences (2024)

Major Depressive Disorder (MDD) is a significant neurological condition associated with aberrations in brain functional networks. Traditional studies have predominantly analyzed these from a network topology perspective. However, given the ...

DOAJ Open Access (DOAJ) DOI: 10.3390/brainsci14050509