Academic Articles & Research Papers

Evaluation of recombinant activated protein C for severe sepsis at a tertiary academic medical center

Kevin E Anger,1 Jeremy R DeGrado,1 Bonnie C Greenwood,1 Steven A Cohen,2 Paul M Szumita1 1Department of Pharmacy, Brigham and Women’s Hospital, Boston, MA, USA; 2Department of Family Medicine and Population Health, Division of Epidemi...

Automated patient and medication payment method for clinical trials

Barbara P Yawn,1 Suzanne Madison,1 Susan Bertram,1 Wilson D Pace,2 Anne Fuhlbrigge,3 Elliot Israel,3 Dawn Littlefield,1 Margary Kurland,1 Michael E Wechsler41Olmsted Medical Center, Department of Research, Rochester, MN, 2UCDHSC, Department...

Recent Trends in Drug Development and Clinical Trials for Hyperuricemia: A Pharmaprojects-Based Landscape Analysis.

Design of the FRESH-LC study: Caregivers as the agent of change for childhood obesity and chronic disease risk among Latino families.

Design of the FRESH-A study: A randomized controlled trial evaluating telehealth parent-only treatment for autistic youth with overweight/obesity.

Examining photoperiod, chronotype, and adherence as predictors of morning light treatment effects on depression symptoms: A study of five clinical trials.

A Registry-Based Perspective of Interventional Clinical Trials for Duchenne Muscular Dystrophy.

Assessment of readability of gynecologic cancer clinical trials literature at National Cancer Institute-designated Comprehensive Cancer Centers.

Network-Integrated Platform for Clinical Trial Navigation from the New South Wales Early Phase Clinical Trials Alliance.

The global landscape of pediatric monoclonal antibody (mAb) clinical trials: an analysis of ClinicalTrials.gov.

Scoping review of oncology clinical trials nursing: Roles, competencies, and evolving practice in cancer research.

Geographic access to triple negative breast cancer clinical trials: are trials located near patients?

Access to cancer clinical trials in Europe: when trial availability does not match patient need.

Vulnerability index impacts distribution of prostate cancer clinical trials in the United States.

The need for fully-effective federated analytics of data sources for clinical trials.

Canine atopic dermatitis clinical trials: study design and methodological considerations.

Surveillance of FAP: a prospective blinded comparison of capsule endoscopy and other GI imaging to detect small bowel polyps

Abstract Background Familial adenomatous polyposis (FAP) is a hereditary disorder characterized by polyposis along the gastrointestinal tract. Information on adenoma status below the duodenum has previously been restricted due to its inacce...

Effectiveness and cost-effectiveness of community perinatal mental health services on access, experience, recovery/relapse and obstetric and neonate outcomes: the ESMI-II mixed-methods study

Background Perinatal mental health disorders affect one in five mothers during pregnancy or within 2 years post childbirth. These disorders can lead to poor pregnancy and childbirth outcomes and maternal deaths. Additionally, they negativel...

Extracellular vesicles: A dive into their role in the tumor microenvironment and cancer progression

Extracellular vesicles (EVs) encompass a diverse set of membrane-derived particles released from cells and are found in numerous biological matrices and the extracellular space. Specific classes of EVs include apoptotic bodies, exosomes, an...

Enhancing clinician participation in quality improvement training: implementation and impact of an evidence-based initiative to maximise antenatal clinician participation in training regarding women’s alcohol consumption during pregnancy

Abstract Background There are significant challenges in ensuring sufficient clinician participation in quality improvement training. Clinician capability has been identified as a barrier to the delivery of evidence-based care. Clinician tra...