Academic Articles & Research Papers

Pharmacological activities and mechanisms of action of Pogostemon cablin Benth: a review

Abstract Patchouli (“Guanghuoxiang”) or scientifically known as Pogostemon cablin Benth, belonging to the family Lamiaceae, has been used in traditional Chinse medicine (TCM) since the time of the Eastern Han dynasty. In TCM theory, patchou...

Endothelial glycocalyx dysfunction in the setting of mechanical thrombectomy: a conceptual link between cardiometabolic vulnerability and microvascular reperfusion failure.

Madecassic acid orchestrates DDX17-dependent pathway suppression of ferroptosis to mitigate myocardial ischemic/reperfusion injury.

Synthesis and preclinical evaluation of a novel 2-[(18)F]fluoropyridine-bearing rhodamine for myocardial perfusion imaging with PET.

The potential biomarkers of organ transplantation in the era of machine perfusion: Current status, challenges, and future directions.

Revisiting Futility: Normothermic Perfusion Improves Outcomes Across all UK DCD Risk Strata.

Stroke reperfusion in Aotearoa New Zealand: 5-year trends and a comparison of stroke clot retrieval and non-stroke clot retrieval centre presenters.

Brain cytoprotection in acute ischemic stroke in the reperfusion era: neuroimmune networks, clinical evidence, and translational barriers.

Swept source intraoperative OCT angiography

To accurately guide surgical instruments during ophthalmic procedures, some necessary intraoperative depth perception is required, which standard surgical microscopes supply limitedly. Intraoperative optical coherence tomography (iOCT), com...

PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway

Background. Hepatic ischemia-reperfusion (IR) injury is one of the severe complications associated with liver surgery and leads to liver dysfunction. PPARγ is always linked with various physiologic pathways, and it can alleviate liver damag...

Early Retinal Microvascular Alterations in Young Type 1 Diabetic Patients without Clinical Retinopathy

The purpose of this study is to identify and quantify preclinical changes with the help of optical coherence tomography angiography (OCTA) within the retinal microcirculation of young type 1 diabetes (T1D) patients without clinical signs of...

Brain perfusion imaging in neonates

Abnormal variations of the neonatal brain perfusion can result in long-term neurodevelopmental consequences and cerebral perfusion imaging can play an important role in diagnostic and therapeutic decision-making. To identify at-risk situati...

Inter-Observer Reliability in Myocardial Blood Flow Measurement Using Rb-82-PET/CT

Background/Objectives: Myocardial perfusion PET/CT, e.g., using Rb-82, enables the measurement of absolute myocardial blood flow (MBF) and, hence, the blood flow reserve, which plays a crucial role in the diagnosis of coronary artery diseas...

Emerging Role of Ferroptosis in the Pathogenesis of Ischemic Stroke: A New Therapeutic Target?

Ischemic stroke is one of the main causes of high morbidity, mortality, and disability worldwide; however, the treatment methods are limited and do not always achieve satisfactory results. The pathogenesis of ischemic stroke is complex, def...

Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform

The devastating effects and incurable nature of hereditary and sporadic retinal diseases such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa urgently require the development of new therapeutic strategies. Add...

Associations of carotid flow velocity with cerebral perfusion and cerebral small vessel disease: a community-based prospective study

Abstract Objectives To explore the associations of carotid artery hemodynamic parameters with cerebral perfusion and cerebral small vessel disease (CSVD) in a healthy population. Methods A total of 654 participants from the Kailuan communit...

Feasibility of one-stop multi-energy dynamic photon-counting perfusion CT for resectable HCC evaluation: lesion detection and histopathological correlations.

Spectral-habitat analysis and perfusion fingerprinting on contrast-enhanced ultrasound for characterizing tumor perfusion in breast lesions.

Protective effects of ceria nanoclusters against delayed paraplegia after spinal cord ischemia

Abstract Spinal cord ischemia reperfusion injury (SCIRI) induced delayed paraplegia is a complex complication of thoracoabdominal aortic surgery. Reactive oxygen species (ROS) play a critical role in the pathogenesis of delayed paraplegia, ...

Role of multilayer flow modulator stents in the treatment of arterial aneurysms

Arterial aneurysms remain a significant public health problem because they often result in death when ruptured; therefore, they require immediate medical treatment. Endovascular aneurysm repair (EVAR) has recently become the primary treatme...