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Showing 7 of 7 academic articles

Neural circuitry governing anxious individuals’ mis-allocation of working memory to threat

Daniel M. Stout, Alexander J. Shackman, Walker S. Pedersen, Tara A. Miskovich et al. • Scientific Reports (2017)

Abstract Dispositional anxiety is a trait-like phenotype that confers increased risk for a range of debilitating neuropsychiatric disorders. Like many patients with anxiety disorders, individuals with elevated levels of dispositional anxiet...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-017-08443-7

Identification of brain regions predicting epileptogenesis by serial [18F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy

Vera Russmann, Matthias Brendel, Erik Mille, Angela Helm-Vicidomini et al. • NeuroImage: Clinical (2017)

Excessive activation of inflammatory signaling pathways seems to be a hallmark of epileptogenesis. Positron emission tomography (PET) allows in vivo detection of brain inflammation with spatial information and opportunities for longitudinal...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2017.04.003

Sex-specific frontal-striatal connectivity differences among adolescents with externalizing disorders

Ya Chai, José R. Chimelis-Santiago, Kristy A. Bixler, Matthew Aalsma et al. • NeuroImage: Clinical (2021)

Background: Sex-specific neurobiological underpinnings of impulsivity in youth with externalizing disorders have not been well studied. The only report of functional connectivity (FC) findings in this area demonstrated sex differences in fr...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102789

Circular RNA expression profiles and functional predication after restraint stress in the amygdala of rats

Chuan Wang, Qian Wang, Guangming Xu, Guangming Xu et al. • Frontiers in Molecular Neuroscience (2024)

Prolonged or repeated exposure to stress elevates the risk of various psychological diseases, many of which are characterized by central nervous system dysfunction. Recent studies have demonstrated that circular RNAs (circRNAs) are highly a...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2024.1381098

Humanized substitutions of Vmat1 in mice alter amygdala-dependent behaviors associated with the evolution of anxiety

Daiki X. Sato, Yukiko U. Inoue, Nahoko Kuga, Satoko Hattori et al. • iScience (2022)

Summary: The human vesicular monoamine transporter 1 (VMAT1) harbors unique substitutions (Asn136Thr/Ile) that affect monoamine uptake into synaptic vesicles. These substitutions are absent in all known mammals, suggesting their contributio...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.isci.2022.104800