Academic Articles & Research Papers

Hyperglycemia impairs cognitive function by inducing mitochondrial damage through lactylation of LRPPRC at K223.

Development of Elective Flexibility and Related Cognitive Functions Across Three Cultures.

Oral microbiome signatures of ageing and cognitive function across distinct geographical cohorts.

Loneliness and cognitive function in later life: a population-based counterfactual analysis.

Exploring the pathways between green space and blue space, and cognitive function in later life: a mediation analysis in Northern Ireland.

Association of childhood meat consumption with late-life cognitive function: mediation by adult education and moderation by parental literacy.

CuddleCard: Protocol for a randomized controlled trial evaluating the effect of providing financial support to low-income mothers of preterm infants on parental caregiving in the neonatal intensive care unit (NICU)

Abstract Background Preterm birth is a leading cause of childhood mortality and developmental disabilities, with persistent socioeconomic disparities in incidence and outcomes. Maternal presence during prolonged neonatal intensive care unit...

Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice

Summary: Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compar...

The interplay of risk factors for future falls and fall-related injuries among community-dwelling older adults: a Bayesian network analysis

Abstract Background Falls are a leading global cause of injury and mortality in older adults, necessitating understanding risk factor interplay for prevention. This study aims to investigate complex interactions among risk factors associate...

Predictivity of bioimpedance phase angle for incident disability in older adults

Abstract Background Bioelectrical impedance analysis (BIA)‐derived phase angle is expected to be an efficient prognostic marker of health adverse events with aging as an alternative of muscle mass. We aimed to examine the predictive ability...

Comparative efficacy of exercise interventions for cognitive health in older adults: A network meta-analysis

Background: Previous studies have consistently demonstrated that exercise mitigates cognitive decline in older adults. However, the most effective types of exercise, along with optimal frequency and duration of interventions, remain inadequ...

Acute cognitive effects of interruptions to prolonged sitting with brief standing or physical activity breaks: a systematic review and three-level meta-analysis

Abstract Background Prolonged sitting is strongly associated with impaired cognitive function. Although traditional exercise interventions have been shown to improve cognitive outcomes, their implementation is often limited by practical con...

Association of inflammation and cognition in the elderly: A systematic review and meta-analysis

BackgroundThe development of mild cognitive impairment (MCI) and Alzheimer’s disease (AD) may be associated with an inflammatory process. Inflammatory cytokines may be a surrogate for systemic inflammation leading to worsening neurological ...

Scrolling and Self: How Self-Esteem and Physical Activity Shape the Effects of Intagram Use on Eating Behavior in Universitary Students

Introduction The use of Social Networking Sites (SNS) has been continuously increasing in recent years [1], contributing to the rise of significant behavioral and psychological issues, especially when SNS are used as a coping mechanism f...

Effect of probiotics on cognitive function and cardiovascular risk factors in mild cognitive impairment and Alzheimer’s disease: an umbrella meta-analysis

Abstract Background This umbrella meta-analysis evaluates the effects of probiotics on cognitive function and metabolic health in Alzheimer’s disease (AD) and mild cognitive impairment (MCI) by synthesizing findings from meta-analyses of ra...

The neuropsychological impact of early childhood trauma on cognitive development: A narrative review of mechanisms, outcomes, and interventions

Abstract Research indicates that early traumatic experiences can profoundly affect a child's ability to manage emotions, develop social skills, and adapt effectively. Still, the impact of trauma on children goes beyond just emotional and be...

The effects of anodal transcranial direct current stimulation on psychological factors in athletes: a systematic review and meta-analysis

Abstract Objective Transcranial direct current stimulation (tDCS) is a safe, non-invasive neuromodulation method that delivers a low-intensity, constant direct current through electrodes positioned on the scalp. Therefore, the purpose of th...

Brain‐Penetrating and Disease Site‐Targeting Manganese Dioxide‐Polymer‐Lipid Hybrid Nanoparticles Remodel Microenvironment of Alzheimer's Disease by Regulating Multiple Pathological Pathways

Abstract Finding effective disease‐modifying treatment for Alzheimer's disease remains challenging due to an array of factors contributing to the loss of neural function. The current study demonstrates a new strategy, using multitargeted bi...

Total mercury exposure in early pregnancy has no adverse association with scholastic ability of the offspring particularly if the mother eats fish

There is a public perception that relatively low doses of mercury found in seafood are harmful to the fetal brain but little consistent evidence to support this. In earlier publications we have shown no adverse associations between maternal...

Making Sense of Bullying: Brooding and subsequent sleep problems in seemingly safe work environments

Abstract Background Work and sleep mutually influence one another: adequate sleep supports cognitive functioning and social regulation at work, whereas safe and respectful working conditions facilitate recovery and sleep. Although workplace...