Academic Articles & Research Papers

Investigating cardiorespiratory fitness, cerebral blood flow, and brain metabolism in epilepsy.

Proton Pump Inhibitor Use and Incident Epilepsy in the UK Biobank: Evidence From Pharmacovigilance and Multi-Omics Analyses.

Recommendations for the re-analysis of existing genomic data from patients with epilepsy.

Population-specific differences in ClinVar pathogenic and likely pathogenic variants of epilepsy-associated genes between East Asian and non-finnish European populations: a nucleotide-resolved gnomAD v4.1.1 analysis.

Global trends in epilepsy and the Chinese experience: Epidemiological transitions, underlying mechanisms, and integrated strategies (1990-2021).

The association between maternal diabetes and the risk of epilepsy in offspring: a systematic review and meta-analysis.

From Recommendations to Practice: Contextualizing the AES/CNS Epilepsy Surgery Guidelines for the Clinician.

Assessing Sudden Unexpected Death in Epilepsy (SUDEP), Mortality, and Suicide in Pediatric Epilepsy from the lens of Healthcare Disparities: Data From a Scoping Review.

American Epilepsy Society/Congress of Neurological Surgeons Epilepsy Surgery Clinical Practice Guideline.

Seizures and epilepsy in MOG antibody-associated disease: from cortical neuroimmunology to clinical practice.

A Case Report of Gabapentin-induced Psychotic Disorder

Gabapentin was first approved for treatment of epilepsy by FDA, but later it received more attention due to its effects on pain relief, especially neuropathic pain and post-herpetic neuralgia, and in treatment of anxiety and insomnia. The m...

The burden and determinants of cognitive impairment among individuals with chronic diseases in Ethiopia: A systematic review and meta-analysis

Introduction: Cognitive impairment is a medical condition caused by neurodegeneration, marked by a gradual decline in neurological, motor, psychological, and cognitive domain functions, as well as daily activities. It primarily affects indi...

De novo SCN1A missense variant in a patient with Parkinson’s disease

BackgroundVariants in a gene encoding sodium voltage-gated channel alpha subunit 1 (SCN1A) are known to cause a broad clinical spectrum of epilepsy and associated features, including Dravet syndrome (MIM 607208), non-Dravet developmental an...

Cracking rare disorders: a new minimally invasive RNA-seq protocol

Abstract RNA sequencing (RNA-seq) has become key to complementing exome and genome sequencing for variant interpretation. We present a minimally invasive RNA-seq protocol using short-term cultured peripheral blood mononuclear cells (PBMCs) ...

Correction: Aging, the microbiota–gut–brain axis, and late-life epilepsy: a hypothesis-driven review

Identification of brain regions predicting epileptogenesis by serial [18F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy

Excessive activation of inflammatory signaling pathways seems to be a hallmark of epileptogenesis. Positron emission tomography (PET) allows in vivo detection of brain inflammation with spatial information and opportunities for longitudinal...

A neural-network-based detection of epilepsy

Diagnosis of epilepsy is primarily based on scalp-recorded electroencephalograms (EEG). Unfortunately the long-term recordings obtained from 'ambulatory recording systems' contain EEG data of up to one week duration, which has introduced ne...

Case Report: Tocilizumab in pediatric febrile infection-related epilepsy syndrome

Background and purposeWe describe the clinical characteristics and the therapeutic effect of tocilizumab with Febrile Infection-Related Epilepsy Syndrome (FIRES). FIRES is characterized by super refractory status epilepticus (SRSE) in previ...

The SIK1-NR4A2 axis: a core driver of epilepsy identified by integrated machine learning and experimental validation.

A role for neural modeling in the study of brain disorders: Comment on From intracerebral EEG signals to brain connectivity: identification of epileptogenic networks in partial epilepsy by F. Wendling et al.