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Advances in the Development of PET Ligands Targeting Histone Deacetylases for the Assessment of Neurodegenerative Diseases

Tetsuro Tago, Jun Toyohara • Molecules (2018)

Epigenetic alterations of gene expression have emerged as a key factor in several neurodegenerative diseases. In particular, inhibitors targeting histone deacetylases (HDACs), which are enzymes responsible for deacetylation of histones and ...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules23020300