Home » Authors » Mansooreh Jaberipour, Simon O. Vass, Christopher P. Guise, Jane I. Grove, Richard J. Knox, Longqin Hu, Eva I. Hyde, Peter F. Searle

Mansooreh Jaberipour, Simon O. Vass, Christopher P. Guise, Jane I. Grove, Richard J. Knox, Longqin Hu, Eva I. Hyde, Peter F. Searle

Public reference bibliography and cataloged PDF materials authored or published by Mansooreh Jaberipour, Simon O. Vass, Christopher P. Guise, Jane I. Grove, Richard J. Knox, Longqin Hu, Eva I. Hyde, Peter F. Searle.

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Testing double mutants of the enzyme nitroreductase for enhanced cell sensitisation to prodrugs: effects of combining beneficial single mutations

Year: 2009 • Source: hal.science • Listed PDF

Prodrug activation gene therapy for cancer involves expressing prodrug-activating enzymes in tumour cells, so they can be selectively killed by systemically administered prodrug. For example, nitroreductase (E.C. 1.6.99....