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Nathalie Lagarde

Public reference bibliography and cataloged PDF materials authored or published by Nathalie Lagarde.

Found 3 document(s) Page 1 of 1

A Promising Approach to Target Colorectal Cancer Using Hybrid Triarylmethanes

Year: 2024 • Source: hal.science • Listed PDF

Abstract Aiming to create an innovative series of anti‐colorectal cancer agents, we designed in this work hybrid triarylmethane compounds. Three hybrid triarylmethanes and their corresponding N ‐oxide analogues were succ...
Predicting Potential Endocrine Disrupting Chemicals Binding to Estrogen Receptor α (ERα) Using a Pipeline Combining Structure-Based and Ligand-Based in Silico Methods

Year: 2021 • Source: hal.science • Listed PDF

The estrogen receptors α (ERα) are transcription factors involved in several physiological processes belonging to the nuclear receptors (NRs) protein family. Besides the endogenous ligands, several other chemicals are ab...
Méthodes de criblage virtuel in silico : importance de l’évaluation et application à la recherche de nouveaux inhibiteurs de l’interleukine 6.

Year: 2014 • Source: hal.science • Listed PDF

Le criblage virtuel est largement employé pour la recherche de nouveaux médicaments.La sélection de structures pour les méthodes de criblage virtuel basées sur la structure reste problématique. Nous avons montré que les ...