Redefining common and rare HTRA1 variants as risk factors for polyvascular disease
Overview & Synopsis
Rare and common variants in HTRA1 are associated with ischemic stroke. Research now sheds light on the underlying genetic architecture and suggests a vasculopathy with a broader phenotypic spectrum. Lower HTRA1 protease activity and circulating levels both predict an increased risk of ischemic stroke and coronary artery disease.
Indexed from repository: HAL Open Science
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hal.science)
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Document Information
| Document Title | Redefining common and rare HTRA1 variants as risk factors for polyvascular disease |
|---|---|
| Author / Organization | Stéphanie Debette, Masafumi Ihara |
| Subject & Discipline | Multidisciplinary Academic Open Research |
| Categories | Science & Mathematics |
| Publication Year | 2024 |
| License / Rights | Open Access / Creative Commons |
| Resource Verification | Listed PDF (Verification Pending) |
| Original Host Website |
HAL Open Science
(hal.science)
|
| File Format | application/pdf (Portable Document Format) |
| Language | EN |
| Catalog ID | DOC-213138 |
| Original Source Link | Visit Source Page on hal.science » |