Changing Contact Patterns Over Disease Progression: Nipah Virus as a Case Study
Overview & Synopsis
Contact patterns play a key role in disease transmission, and variation in contacts during the course of illness can influence transmission, particularly when accompanied by changes in host infectiousness. We used surveys among 1642 contacts of 94 Nipah virus case patients in Bangladesh to determine how contact patterns (physical and with bodily fluids) changed as disease progressed in severity. The number of contacts increased with severity and, for case patients who died, peaked on the day of death. Given transmission has only been observed among fatal cases of Nipah virus infection, our findings suggest that changes in contact patterns during illness contribute to risk of infection.
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Document Information
| Document Title | Changing Contact Patterns Over Disease Progression: Nipah Virus as a Case Study |
|---|---|
| Author / Organization | Kyu Han Lee, Birgit Nikolay, Hossain Sazzad, M Jahangir Hossain, A Khan, Mahmudur Rahman, Syed Moinuddin Satter, Stuart Nichol, John Klena, Juliet Pulliam, A Marm Kilpatrick, Sharmin Sultana, Sayma Afroj, Peter Daszak, Stephen Luby, Simon Cauchemez, Henrik Salje, Emily Gurley |
| Subject & Discipline | Multidisciplinary Academic Open Research |
| Categories | Science & Mathematics |
| Publication Year | 2020 |
| License / Rights | Open Access / Creative Commons |
| Resource Verification | Listed PDF (Verification Pending) |
| Original Host Website |
HAL Open Science
(hal.science)
|
| File Format | application/pdf (Portable Document Format) |
| Language | EN |
| Catalog ID | DOC-251815 |
| Original Source Link | Visit Source Page on hal.science » |